Gradient-Based Pulsed Excitation and Relaxation Encoding in Magnetic Particle Imaging
文献类型：期刊论文
| 作者 | Jia, Guang11; Huang, Liyu10; Wang, Ze11; Liang, Xiaofeng11; Zhang, Yu11; Zhang, Yifei11; Miao, Qiguang11; Hu, Kai9; Li, Tanping9; Wang, Ying8 |
| 刊名 | IEEE TRANSACTIONS ON MEDICAL IMAGING
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| 出版日期 | 2022-12-01 |
| 卷号 | 41期号:12页码:3725-3733 |
| 关键词 | Magnetic particle imaging pulsed excitation gradient field field free line spatial encoding tomography magnetic nanoparticles Debye relaxation time system matrix singular value decomposition |
| ISSN号 | 0278-0062 |
| DOI | 10.1109/TMI.2022.3193219 |
| 通讯作者 | Jia, Guang(gjia@xidian.edu.cn) ; Li, Tanping(tpli@xidian.edu.cn) ; Tian, Jie(tian@ieee.org) |
| 英文摘要 | Magnetic particle imaging (MPI) is a radiationfree vessel- and target-imaging modality that can sensitively detect nanoparticles. A static magnetic gradient field, referred to as a selection field, is required in MPI to provide a field-free region (FFR) for spatial encoding. The image resolution of MPI is closely related to the size of the FFR, which is determined by the selection field gradient amplitude. Because of the limitations of existing gradient coil hardware, the image resolution of MPI cannot satisfy the clinical requirements of human in vivo imaging. Pulsed excitation has been confirmed to improve the image resolution of MPI by breaking down the `relaxation wall.' This work proposes the use of a pulsed waveform magnetic gradient from magnetic resonance imaging to further improve the image resolution of MPI. Through alignment of the gradient direction along the field-free line (FFL), each location on the FFL is able to have a unique excitation field strength that generates a specific relaxation-induced decay signal. Through excitation of nanoparticles on the FFL with many gradient profiles, a high-resolution, one-dimensional (1D) image can be reconstructed on the FFL. For larger magnetic nanoparticles, simulation results revealed that a pulsed excitation field with a greater flat portion generates a 1D bar pattern phantom image with a higher correlation and spatial resolution. With parallel FFL and gradient coil movements, high-resolution, two-dimensional (2D) SheppLogan phantom and brain vessel maps were reconstructed through repetition of the spatially resolvedmeasurement of magnetic nanoparticles on the FFL. |
| WOS关键词 | IRON-OXIDE NANOPARTICLES ; SENSITIVITY ; RESOLUTION ; MAGNETORELAXOMETRY ; INVERSION ; FIELDS |
| 资助项目 | National Key Research and Development Program of China[2017YFA0700401] ; National Natural Science Foundation of China[62027901] ; National Natural Science Foundation of China[11974267] ; 111 Project[B17035] |
| WOS研究方向 | Computer Science ; Engineering ; Imaging Science & Photographic Technology ; Radiology, Nuclear Medicine & Medical Imaging |
| 语种 | 英语 |
| WOS记录号 | WOS:000907324600021 |
| 出版者 | IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC |
| 资助机构 | National Key Research and Development Program of China ; National Natural Science Foundation of China ; 111 Project |
| 源URL | [http://ir.ia.ac.cn/handle/173211/51141]  |
| 专题 | 自动化研究所_中国科学院分子影像重点实验室 |
| 通讯作者 | Jia, Guang; Li, Tanping; Tian, Jie |
| 作者单位 | 1.Jinan Univ, Zhuhai Peoples Hosp, Zhuhai Precis Med Ctr, Zhuhai 519000, Peoples R China 2.Chinese Acad Sci, Beijing Key Lab Mol Imaging, Inst Automat, Beijing 100190, Peoples R China 3.Chinese Acad Sci, CAS Key Lab Mol Imaging, Beijing 100190, Peoples R China 4.Beihang Univ, Beijing Adv Innovat Ctr Big Data Based Precis Med, Sch Engn Med, Beijing 100083, Peoples R China 5.Univ Chinese Acad Sci, Sch Artificial Intelligence, Beijing 100080, Peoples R China 6.Chinese Acad Sci, Inst Automat, State Key Lab Management & Control Complex Syst, Beijing 100190, Peoples R China 7.Chinese Acad Sci, CAS Key Lab Mol Imaging, Beijing Key Lab Mol Imaging, Beijing 100190, Peoples R China 8.Lanzhou Univ, Sch Phys Sci & Technol, Lanzhou 730000, Gansu, Peoples R China 9.Xidian Univ, Sch Phys, Xian 710071, Shaanxi, Peoples R China 10.Xidian Univ, Sch Life Sci & Technol, Xian 710071, Shaanxi, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jia, Guang,Huang, Liyu,Wang, Ze,et al. Gradient-Based Pulsed Excitation and Relaxation Encoding in Magnetic Particle Imaging[J]. IEEE TRANSACTIONS ON MEDICAL IMAGING,2022,41(12):3725-3733. |
| APA | Jia, Guang.,Huang, Liyu.,Wang, Ze.,Liang, Xiaofeng.,Zhang, Yu.,...&Tian, Jie.(2022).Gradient-Based Pulsed Excitation and Relaxation Encoding in Magnetic Particle Imaging.IEEE TRANSACTIONS ON MEDICAL IMAGING,41(12),3725-3733. |
| MLA | Jia, Guang,et al."Gradient-Based Pulsed Excitation and Relaxation Encoding in Magnetic Particle Imaging".IEEE TRANSACTIONS ON MEDICAL IMAGING 41.12(2022):3725-3733. |
入库方式： OAI收割
来源：自动化研究所
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