Dual pH and Temperature-Sensitive Nanogels Loaded with Eugenol for Regulating Central Nervous System
文献类型：期刊论文
| 作者 | Li, Yan2; Wang, Jing-Wen1,3; Dong, Qiu-Shi4; Zhao, Bao-Chang1; Zhang, Ji-Mei1; Li, Yan-Ling1; Lu, Zhi-Guo3; Zhang, Xin3 |
| 刊名 | JOURNAL OF BIOMEDICAL NANOTECHNOLOGY
 |
| 出版日期 | 2022-03-01 |
| 卷号 | 18期号:3页码:860-867 |
| 关键词 | Eugenol Nano-Fragrance Dual pH and Temperature-Sensitive Nanogels EG@CPMO-NGs The Effects on the Central Nervous System |
| ISSN号 | 1550-7033 |
| DOI | 10.1166/jbn.2022.3289 |
| 英文摘要 | Fragrances have many biological activities such as anti-anxiety, anti-depression, and improving cognitive memory. However, most fragrances are so volatile that the useful lifespan of the fragrances is very short and excessive fragrance concentration makes us uncomfortable. In this study, dual pH and temperature-sensitive nanogels named EG@CPMONGs were prepared to encapsulate eugenol. This nano-fragrance was then applied to silk. In the following, the effects of EG@CPMO-NGs on the regulation of central nervous systems were evaluated. Open-field tests showed that EG@CPMONGs had an obvious effect on stress relief. Elevated plus-maze tests proved the significant effect of EG@CPMO-NGs on anti-anxiety. Morris water maze tests demonstrated the positive impact of nano-fragrance on spatial learning and memory. IP 1498 16066 On: Wed 22 Jun 2022 06:31:22 Therefore, these dual pH and temperature-sensiive nanogels loaded with eugenol had significant and positive effects on Copyright: American Scient fic Publishe s the central nervous system. |
| WOS关键词 | MORRIS WATER MAZE ; ESSENTIAL OILS ; DRUG-DELIVERY ; OPEN-FIELD ; FRAGRANCE ; NANOPARTICLES ; ENHANCEMENT ; LIPOSOMES ; RELEASE ; ANXIETY |
| 资助项目 | China Postdoctoral Science Foundation[2021M703240] ; National Natural Science Foundation of China[22075289] ; National Natural Science Foundation of China[31771095] ; National Natural Science Foundation of China[21875254] ; National Natural Science Foundation of China[21905283] ; Fundamental Research Funds for the Central Universities[06500230] |
| WOS研究方向 | Science & Technology - Other Topics ; Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000815143400001 |
| 出版者 | AMER SCIENTIFIC PUBLISHERS |
| 资助机构 | China Postdoctoral Science Foundation ; National Natural Science Foundation of China ; Fundamental Research Funds for the Central Universities |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/54024]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Li, Yan-Ling; Lu, Zhi-Guo; Zhang, Xin |
| 作者单位 | 1.Shandong First Med Univ & Shandong Acad Med Sci, Tai An 271016, Shandong, Peoples R China 2.Univ Sci & Technol Beijing, Sch Chem & Biol Engn, Beijing 100083, Peoples R China 3.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 4.Beijing Canc Hosp, Beijing 100142, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Yan,Wang, Jing-Wen,Dong, Qiu-Shi,et al. Dual pH and Temperature-Sensitive Nanogels Loaded with Eugenol for Regulating Central Nervous System[J]. JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,2022,18(3):860-867. |
| APA | Li, Yan.,Wang, Jing-Wen.,Dong, Qiu-Shi.,Zhao, Bao-Chang.,Zhang, Ji-Mei.,...&Zhang, Xin.(2022).Dual pH and Temperature-Sensitive Nanogels Loaded with Eugenol for Regulating Central Nervous System.JOURNAL OF BIOMEDICAL NANOTECHNOLOGY,18(3),860-867. |
| MLA | Li, Yan,et al."Dual pH and Temperature-Sensitive Nanogels Loaded with Eugenol for Regulating Central Nervous System".JOURNAL OF BIOMEDICAL NANOTECHNOLOGY 18.3(2022):860-867. |
入库方式： OAI收割
来源：过程工程研究所
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