Peptide-based supramolecular assembly drugs toward cancer theranostics
文献类型：期刊论文
| 作者 | Li, Shukun1,3; Xing, Ruirui3,4; van Hest, Jan C. M.1; Yan, Xuehai2,3,4 |
| 刊名 | EXPERT OPINION ON DRUG DELIVERY
 |
| 出版日期 | 2022-07-03 |
| 页码 | 14 |
| ISSN号 | 1742-5247 |
| 关键词 | Peptide-based particles drug assemblies programmable design cancer theranostics |
| DOI | 10.1080/17425247.2022.2093855 |
| 英文摘要 | Introduction Peptide-based supramolecular self-assembly has been demonstrated to be a flexible approach for the fabrication of programmable de novo nanodrugs by employing synergistic or reciprocal intermolecular non-covalent interactions. This class of nanomaterials holds significant promise for clinical translation, especially as cancer theranostics. Areas covered In this review, we describe the concept of cancer theranostic drug assembly by employing non-covalent interactions. That is, molecular drugs are formulated into nanoscale and even microscale architectures by peptide-modulated self-assembly. A series of peptide-based supramolecular assembly drugs are discussed, with an emphasis on the relation between structural feature and theranostic performance. Expert opinion Molecular design, manipulation of non-covalent interactions, and elucidation of structure-function relationships not only facilitate the implementation of supramolecular self-assembly principles in drug development, but also provide a new means for advancing anticancer nanostructured drugs toward clinical application. |
| WOS关键词 | THERAPEUTICS ; NANOMATERIALS ; PRINCIPLES ; MECHANISM ; HYDROGELS ; STRATEGY ; DELIVERY ; DESIGN |
| 资助项目 | National Science Fund for Distinguished Young Scholars of China[22025207] ; Innovation Research Community Science Fund of China[21821005] ; National Natural Science Foundation of China[22072154] ; International Postdoctoral Exchange Fellowship Program of the Office of China Postdoctoral Council[PC2021079] ; National Natural Science Foundation of Hebei Province[B2020103025] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | TAYLOR & FRANCIS LTD |
| WOS记录号 | WOS:000820731200001 |
| 资助机构 | National Science Fund for Distinguished Young Scholars of China ; Innovation Research Community Science Fund of China ; National Natural Science Foundation of China ; International Postdoctoral Exchange Fellowship Program of the Office of China Postdoctoral Council ; National Natural Science Foundation of Hebei Province |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/54080]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Yan, Xuehai |
| 作者单位 | 1.Eindhoven Univ Technol, Inst Complex Mol Syst, Bioorgan Chem, Eindhoven, Netherlands 2.Chinese Acad Sci, Inst Proc Engn, Ctr Mesosci, Beijing, Peoples R China 3.Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 4.Univ Chinese Acad Sci, Sch Chem Engn, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Shukun,Xing, Ruirui,van Hest, Jan C. M.,et al. Peptide-based supramolecular assembly drugs toward cancer theranostics[J]. EXPERT OPINION ON DRUG DELIVERY,2022:14. |
| APA | Li, Shukun,Xing, Ruirui,van Hest, Jan C. M.,&Yan, Xuehai.(2022).Peptide-based supramolecular assembly drugs toward cancer theranostics.EXPERT OPINION ON DRUG DELIVERY,14. |
| MLA | Li, Shukun,et al."Peptide-based supramolecular assembly drugs toward cancer theranostics".EXPERT OPINION ON DRUG DELIVERY (2022):14. |
入库方式： OAI收割
来源：过程工程研究所
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