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Extraction, Physicochemical Properties, Anti-Aging, and Antioxidant Activities of Polysaccharides from Industrial Hemp Residues

文献类型：期刊论文

作者Chang, Tanran1,2; Li, Hang1,2; Lv, Hongning1; Tan, Minghui3; Hou, Shoubu1,2; Liu, Xu4; Lian, Meng4; Zhao, Qingsheng1,2; Zhao, Bing1
刊名MOLECULES
出版日期2022-09-01
卷号27期号:18页码:17
关键词industrial hemp polysaccharide extraction antioxidant activity anti-aging activity
DOI10.3390/molecules27185746
英文摘要A large amount of hemp polysaccharides remain in industrial hemp residues (IHR) after cannabidiol extraction, resulting in the waste of resources. Therefore, the systematic study of hemp polysaccharides is beneficial to the development of IHR in the future. In this study, the extraction of industrial hemp residues polysaccharide (IHRPs) was optimized by single-factor experiment and orthogonal experimental design. The optimum heating extraction conditions were extraction temperature 98 degrees C, solid-liquid ratio 1:10, extraction time 1 h, number of successive extractions 2, and pH at 4. The extraction ratio and the polysaccharide content were 20.12 +/- 0.55% and 12.35 +/- 0.26% at the conditions, respectively. Besides, the best alcohol precipitation conditions were pumping with 2 L/h, stirring continuously, and ice-water bath for 4 h. The crude IHRPs was further purified by column chromatography and the polysaccharide/protein contents of purified IHRPs were 34.44% and 1.61%. IHRPs was mainly made up of ten monosaccharides and some non-sugar components including organic acids, flavonoids, steroids, and glycoside. The FT-IR demonstrated the polysaccharide skeleton of IHRPs. Moreover, the DPPH and ABTS scavenging rate of IHRPs were 76.00% and 99.05% at the concentrations of 1 mg/mL. IHRPs could promote the epidermal cells proliferation and healing of cell scratches. Meanwhile, IHRPs could promoted the expression of anti-aging-related genes. Overall, IHRPs could be a desirable natural source of antioxidants and anti-aging products in many aspects.
WOS关键词ENTEROMORPHA-PROLIFERA ; CANNABIS ; WATER
资助项目Yunnan Hempmon Pharmaceuticals Co., Ltd.
WOS研究方向Biochemistry & Molecular Biology ; Chemistry
语种英语
WOS记录号WOS:000858826300001
出版者MDPI
资助机构Yunnan Hempmon Pharmaceuticals Co., Ltd.
源URL[http://ir.ipe.ac.cn/handle/122111/54679]  
专题中国科学院过程工程研究所
通讯作者Zhao, Qingsheng; Zhao, Bing
作者单位1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Guangdong Ocean Univ, Coll Food Sci & Technol, Zhanjiang 524088, Peoples R China
4.Yunnan Hempmon Pharmaceut Co Ltd, Kunming 650032, Yunnan, Peoples R China
推荐引用方式
GB/T 7714		 Chang, Tanran,Li, Hang,Lv, Hongning,et al. Extraction, Physicochemical Properties, Anti-Aging, and Antioxidant Activities of Polysaccharides from Industrial Hemp Residues[J]. MOLECULES,2022,27(18):17.
APA Chang, Tanran.,Li, Hang.,Lv, Hongning.,Tan, Minghui.,Hou, Shoubu.,...&Zhao, Bing.(2022).Extraction, Physicochemical Properties, Anti-Aging, and Antioxidant Activities of Polysaccharides from Industrial Hemp Residues.MOLECULES,27(18),17.
MLA Chang, Tanran,et al."Extraction, Physicochemical Properties, Anti-Aging, and Antioxidant Activities of Polysaccharides from Industrial Hemp Residues".MOLECULES 27.18(2022):17.

入库方式： OAI收割

来源：过程工程研究所

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