Advances of bacteria-based delivery systems for modulating tumor microenvironment
文献类型：期刊论文
| 作者 | Li, Shuping1,2; Yue, Hua1,3; Wang, Shuang1; Li, Xin1; Wang, Xiaojun4; Guo, Peilin1,3; Ma, Guanghui1,3; Wei, Wei1,3 |
| 刊名 | ADVANCED DRUG DELIVERY REVIEWS
 |
| 出版日期 | 2022-09-01 |
| 卷号 | 188页码:23 |
| ISSN号 | 0169-409X |
| 关键词 | Bacterial carriers TME modulation TME components Hospitable properties Immune tolerance suppression Immune activation Hypoxia |
| DOI | 10.1016/j.addr.2022.114444 |
| 英文摘要 | The components and hospitable properties of tumor microenvironment (TME) are associated with tumor progression. Recently, TME modulating vectors and strategies have garnished significant attention in cancer therapy. Although a pilot work has reviewed TME regulation via nanoparticle-based delivery systems, there is no systematical review that summarizes the natural bacteria-based anti-tumor system to modulate TME. In this review, we conclude the strategies of bacterial carriers (including whole bacteria, bacterial skeleton and bacterial components) to regulate TME from the perspective of TME components and hospitable properties, and the clinical trials of bacteria-mediated cancer therapy. Current challenges and future prospects for the design of bacteria-based carriers are also proposed that provide critical insights into this natural delivery system and related translation from the bench to the clinic. (c) 2022 Elsevier B.V. All rights reserved. |
| WOS关键词 | METASTATIC BREAST-CANCER ; MEMBRANE PROTEIN-A ; LISTERIA-MONOCYTOGENES ; MACROPHAGE POLARIZATION ; MAGNETOTACTIC BACTERIA ; TARGETED DELIVERY ; IMMUNE-RESPONSE ; PHASE-I ; THERAPY ; IMMUNOTHERAPY |
| 资助项目 | National Natural Science Foundation of China[21821005] ; National Natural Science Foundation of China[U2001224] ; National Natural Science Foundation of China[U20A20361] ; Beijing Natural Science Foundation[JQ21027] ; Beijing Natural Science Foundation[2202056] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | ELSEVIER |
| WOS记录号 | WOS:000891299300006 |
| 资助机构 | National Natural Science Foundation of China ; Beijing Natural Science Foundation |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/56101]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Ma, Guanghui; Wei, Wei |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China 2.Jiangnan Univ, Key Lab Carbohydrate Chem & Biotechnol, Minist Educ, Sch Biotechnol, Wuxi 214122, Jiangsu, Peoples R China 3.Univ Chinese Acad Sci, Sch Chem Engn, Beijing 100049, Peoples R China 4.Capital Med Univ, Beijing Chaoyang Hosp, Dept Ophthalmol, Beijing 100020, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Shuping,Yue, Hua,Wang, Shuang,et al. Advances of bacteria-based delivery systems for modulating tumor microenvironment[J]. ADVANCED DRUG DELIVERY REVIEWS,2022,188:23. |
| APA | Li, Shuping.,Yue, Hua.,Wang, Shuang.,Li, Xin.,Wang, Xiaojun.,...&Wei, Wei.(2022).Advances of bacteria-based delivery systems for modulating tumor microenvironment.ADVANCED DRUG DELIVERY REVIEWS,188,23. |
| MLA | Li, Shuping,et al."Advances of bacteria-based delivery systems for modulating tumor microenvironment".ADVANCED DRUG DELIVERY REVIEWS 188(2022):23. |
入库方式： OAI收割
来源：过程工程研究所
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