Textured propyl gallate modified MXene biopaster with prolonged photothermal effect for in-situ post-surgery residual tumor clearance
文献类型：期刊论文
| 作者 | Wang, Xiang1; Sun, Feifei1; Wang, Ya2; Yan, Zidi1; Wang, Xunrui1; Kong, Haoran1; Wang, Yu1 |
| 刊名 | NANO TODAY
 |
| 出版日期 | 2023-02-01 |
| 卷号 | 48页码:11 |
| ISSN号 | 1748-0132 |
| 关键词 | PG-grafting MXene Long-term photothermal responsiveness Residual tumor clearance Tumor recurrence prevention |
| DOI | 10.1016/j.nantod.2022.101701 |
| 英文摘要 | Residual tumors after surgery lead to a high risk of recurrence, and effective strategies clearing the residual tumors urgently need to be developed. Locally administering antitumor agents after surgery has been proved effective to clear residual tumor cells, but achieving long-lasting efficacy and repeatable treatment are still challenges for these agents. In this study, we orderly arranged propyl gallate (PG)-grafting MXene onto calcium-alginate hydrogel (CA) layer to develop a photothermal-responsive biopaster for the tumor post-surgery recurrence prevention. The order arrangement of PG-grafting MXene nanosheets with the prolonged degradation time (compared to the non-PG-grafting ones) could retain the photothermal responsiveness for 14 days. Therefore, this biopaster provided long-term photothermal therapeutic capability to kill the residual tumors and effectively prevented the tumor recurrence (after surgery). This work provides references for designing NIR-responsive 2D nanomaterials with enhanced NIR-responsiveness and long-term antitumor efficacy. (C) 2022 Elsevier Ltd. All rights reserved. |
| WOS关键词 | NANOSHEETS ; THERAPY |
| 资助项目 | National Natural Science Foundation of China[22105206] ; National Natural Science Foundation of China[21875256] ; Youth Project of Beijing Municipal Natural Science Foundation[2214080] ; Key Laboratory of Photochemical Conversion and Optoelectronic Materials, TIPC, CAS[PCOM202112] |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCI LTD |
| WOS记录号 | WOS:000895722300002 |
| 资助机构 | National Natural Science Foundation of China ; Youth Project of Beijing Municipal Natural Science Foundation ; Key Laboratory of Photochemical Conversion and Optoelectronic Materials, TIPC, CAS |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/56116]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Sun, Feifei; Wang, Yu |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Multiphase Complex Syst, Beijing 100190, Peoples R China 2.Tsinghua Univ, Sch Environm, State Key Joint Lab Environm Simulat & Pollut Cont, Beijing 100084, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Xiang,Sun, Feifei,Wang, Ya,et al. Textured propyl gallate modified MXene biopaster with prolonged photothermal effect for in-situ post-surgery residual tumor clearance[J]. NANO TODAY,2023,48:11. |
| APA | Wang, Xiang.,Sun, Feifei.,Wang, Ya.,Yan, Zidi.,Wang, Xunrui.,...&Wang, Yu.(2023).Textured propyl gallate modified MXene biopaster with prolonged photothermal effect for in-situ post-surgery residual tumor clearance.NANO TODAY,48,11. |
| MLA | Wang, Xiang,et al."Textured propyl gallate modified MXene biopaster with prolonged photothermal effect for in-situ post-surgery residual tumor clearance".NANO TODAY 48(2023):11. |
入库方式： OAI收割
来源：过程工程研究所
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