Ruthenium-catalyzed reductive amination of ketones with nitroarenes and nitriles
文献类型：期刊论文
| 作者 | Sun, Rui1,2; Ma, Shuang-Shuang1,2; Zhang, Zi-Heng3,4; Zhang, Yan-Qiang1,2; Xu, Bao-Hua1,2,4 |
| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 出版日期 | 2023-01-10 |
| 页码 | 7 |
| ISSN号 | 1477-0520 |
| DOI | 10.1039/d2ob02312a |
| 英文摘要 | The Ru(dppbsa)-catalyzed reductive amination of ketones with nitroarenes and nitriles using H-2 as the environmentally benign hydrogen surrogate is developed in this study. Cross-experiments demonstrated that both reactions are initiated by the reduction of nitroarenes or nitriles to the corresponding amines, followed by condensation with ketones to give imines and thereafter hydrogenation. However, the route to the formation of an amino-ligated Ru complex during the reduction of nitroarenes or nitriles, followed by in situ nucleophilic C-N coupling, cannot be completely excluded. This newly developed versatile method features good functional group tolerance, which provides a novel design platform for homogeneous catalysts in constructing motifs of secondary amines. |
| WOS关键词 | SECONDARY-AMINES ; CARBONYL-COMPOUNDS ; NITRO-COMPOUNDS ; HYDROGENATION ; NANOPARTICLES ; ALDEHYDES ; GREEN ; CASCADE ; MILD |
| 资助项目 | National Natural Science Foundation of China Youth Fund[22022815] ; Innovation Academy for Green Manufacture, CAS[IAGM2020C13] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:000913310300001 |
| 资助机构 | National Natural Science Foundation of China Youth Fund ; Innovation Academy for Green Manufacture, CAS |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/56506]  |
| 专题 | 中国科学院过程工程研究所 |
| 通讯作者 | Zhang, Yan-Qiang; Xu, Bao-Hua |
| 作者单位 | 1.Chinese Acad Sci, Inst Proc Engn, Beijing Key Lab Ion Liquids Clean Proc, CAS Key Lab Green Proc & Engn,State Key Lab Multip, Beijing 100190, Peoples R China 2.Univ Chinese Acad Sci, Coll Chem & Chem Engn, Beijing 100049, Peoples R China 3.Huaqiao Univ, Coll Mat Sci & Engn, Xiamen 361021, Peoples R China 4.Beijing Inst Technol, Sch Chem & Chem Engn, Beijing Key Lab Chem Power Source & Green Catalysi, Beijing 100081, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Rui,Ma, Shuang-Shuang,Zhang, Zi-Heng,et al. Ruthenium-catalyzed reductive amination of ketones with nitroarenes and nitriles[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2023:7. |
| APA | Sun, Rui,Ma, Shuang-Shuang,Zhang, Zi-Heng,Zhang, Yan-Qiang,&Xu, Bao-Hua.(2023).Ruthenium-catalyzed reductive amination of ketones with nitroarenes and nitriles.ORGANIC & BIOMOLECULAR CHEMISTRY,7. |
| MLA | Sun, Rui,et al."Ruthenium-catalyzed reductive amination of ketones with nitroarenes and nitriles".ORGANIC & BIOMOLECULAR CHEMISTRY (2023):7. |
入库方式： OAI收割
来源：过程工程研究所
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