Negative emotions arising from self-threat are ubiquitous and harmful. We propose that the experience of awe awakens the small-self, which in turn alleviates these negative emotions. We examine our theoretical hypotheses in four studies employing various self-threatening situations, using distinct awe manipulations and involving participants from different countries. The participants experiencing awe reported lower levels of negative emotions arising from self-threat compared with those in the neutral (Study 1) and happiness conditions (Study 2). Moreover, we verified that the small-self mediates the alleviating effect of awe on negative emotions through measuring (Study 3) and manipulating the small-self (Study 4). Beyond a set of practical implications for promoting mental health and well-being, our research also provides novel insights into awe, self-appraisal, and self-threat.