Impacts of Mercury Exposure Levels and Sources on the Demethylation of Methylmercury Through Human Gut Microbiota
文献类型：期刊论文
| 作者 | Xian-Feng Yang; Shao-Chen Yang; Fu-Li Wen; Lin Feng; Bo Meng; Hai-Yan Hu; Bao-Lin Wang; Jun Li; Alexandre J. Poulain; Ping Li |
| 刊名 | Bulletin of Environmental Contamination and Toxicology
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| 出版日期 | 2022 |
| 卷号 | 109页码:534–541 |
| 关键词 | Methylmercury Demethylation Gut Microbiota Exposure Level Exposure Source |
| DOI | 10.1007/s00128-022-03569-5 |
| 英文摘要 | This study aims to investigate methylmercury (MeHg) demethylation processes in human gut. Here, we determined the compositions and MeHg demethylation rates of gut microbiota in residents from different Hg exposure levels (Wanshan (WS) town and Yangtou (YT) town) and different Hg exposure sources (Zhuchang (ZC) town and YT town) regions. MeHg and inorganic Hg exposure levels in residents of WS town were significantly higher than those of YT and ZC town. Desulfovibrio and Methanogens, which related to Hg methylation/demethylation, showed significantly higher abundance in WS and ZC, comparing with YT. In vitro experiments demonstrated that human intestinal microbiota could degrade MeHg directly. Besides, gut microbiota in WS and ZC exhibited significantly higher demethylation rates than YT, suggesting Desulfovibrio and Methanogens may play important roles in intestinal MeHg demethylation. This study highlights Hg exposure levels and sources may affect demethylation efficiency of gut microbiota, which provides new insights for MeHg demethylation processes in human body. |
| URL标识 | 查看原文 |
| 语种 | 英语 |
| 源URL | [http://ir.gyig.ac.cn/handle/42920512-1/13517]  |
| 专题 | 地球化学研究所_环境地球化学国家重点实验室 |
| 作者单位 | 1.School of Public Health, Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, 550025, China 2.Hubei Key Laboratory of Critical Zone Evolution, School of Earth Sciences, China University of Geosciences, Wuhan, 430074, China 3.State Key Laboratory of Environmental Geochemistry, Institute of Geochemistry, Chinese Academy of Sciences, Guiyang, 550081, China 4.Department of Biology, Faculty of Science, University of Ottawa, Ottawa, K1N 6N5, Canada |
| 推荐引用方式 GB/T 7714 | Xian-Feng Yang,Shao-Chen Yang,Fu-Li Wen,et al. Impacts of Mercury Exposure Levels and Sources on the Demethylation of Methylmercury Through Human Gut Microbiota[J]. Bulletin of Environmental Contamination and Toxicology,2022,109:534–541. |
| APA | Xian-Feng Yang.,Shao-Chen Yang.,Fu-Li Wen.,Lin Feng.,Bo Meng.,...&Ping Li.(2022).Impacts of Mercury Exposure Levels and Sources on the Demethylation of Methylmercury Through Human Gut Microbiota.Bulletin of Environmental Contamination and Toxicology,109,534–541. |
| MLA | Xian-Feng Yang,et al."Impacts of Mercury Exposure Levels and Sources on the Demethylation of Methylmercury Through Human Gut Microbiota".Bulletin of Environmental Contamination and Toxicology 109(2022):534–541. |
入库方式： OAI收割
来源：地球化学研究所
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