中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
MSMFN: An ultrasound based multi-step modality fusion network for identifying the histologic subtypes of metastatic cervical lymphadenopathy

文献类型:期刊论文

作者Zheling, Meng2,3; Yangyang, Zhu1; Wenjing, Pang1; Jie, Tian2,3; Fang, Nie1; Kun, Wang2,3
刊名IEEE Transactions on Medical Imaging
出版日期2022-11
页码1-13
文献子类SCI
英文摘要

Identifying squamous cell carcinoma and adenocarcinoma subtypes of metastatic cervical lymphadenopathy (CLA) is critical for localizing the primary lesion and initiating timely therapy. B-mode ultrasound (BUS), color Doppler flow imaging (CDFI), ultrasound elastography (UE) and dynamic contrast-enhanced ultrasound provide effective tools for identification but synthesis of modality information is a challenge for clinicians. Therefore, based on deep learning, rationally fusing these modalities with clinical information to personalize the classification of metastatic CLA requires new explorations. In this paper, we propose Multi-step Modality Fusion Network (MSMFN) for multi-modal ultrasound fusion to identify histological subtypes of metastatic CLA. MSMFN can mine the unique features of each modality and fuse them in a hierarchical three-step process. Specifically, first, under the guidance of high-level BUS semantic feature maps, information in CDFI and UE is extracted by modality interaction, and the static imaging feature vector is obtained. Then, a self-supervised feature orthogonalization loss is introduced to help learn modality heterogeneity features while maintaining maximal task-consistent category distinguishability ofmodalities. Finally, six encoded clinical information are utilized to avoid prediction bias and improve prediction ability further. Our three-fold cross-validation experiments demonstrate that our method surpasses clinicians and other multi-modal fusion methods with an accuracy of 80.06%, a true-positive rate of 81.81%, and a true-negative rate of 80.00%. Our network provides a multi-modal ultrasound fusion framework that considers prior clinical knowledge and modality-specific characteristics. Our code will be available at: https://github.com/RichardSunnyMeng/MSMFN.

语种英语
源URL[http://ir.ia.ac.cn/handle/173211/51470]  
专题自动化研究所_中国科学院分子影像重点实验室
通讯作者Fang, Nie; Kun, Wang
作者单位1.兰州大学第二医院
2.中国科学院大学人工智能学院
3.中国科学院自动化研究所
推荐引用方式
GB/T 7714
Zheling, Meng,Yangyang, Zhu,Wenjing, Pang,et al. MSMFN: An ultrasound based multi-step modality fusion network for identifying the histologic subtypes of metastatic cervical lymphadenopathy[J]. IEEE Transactions on Medical Imaging,2022:1-13.
APA Zheling, Meng,Yangyang, Zhu,Wenjing, Pang,Jie, Tian,Fang, Nie,&Kun, Wang.(2022).MSMFN: An ultrasound based multi-step modality fusion network for identifying the histologic subtypes of metastatic cervical lymphadenopathy.IEEE Transactions on Medical Imaging,1-13.
MLA Zheling, Meng,et al."MSMFN: An ultrasound based multi-step modality fusion network for identifying the histologic subtypes of metastatic cervical lymphadenopathy".IEEE Transactions on Medical Imaging (2022):1-13.

入库方式: OAI收割

来源:自动化研究所

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