Development of Testis Cords and the Formation of Efferent Ducts in Xenopus laevis: Differences and Similarities with Other Vertebrates
文献类型：期刊论文
| 作者 | Li, Yuanyuan; Li, Jinbo ; Cai, Man; Qin, Zhanfen
|
| 刊名 | SEXUAL DEVELOPMENT
 |
| 出版日期 | 2021-07 |
| 卷号 | 14期号:1-6页码:66-79 |
| ISSN号 | 1661-5425 |
| 关键词 | Cell differentiation Cell migration Cell proliferation Efferent duct Testis cord |
| 英文摘要 | The knowledge of testis development in amphibians relative to amniotes remains limited. Here, we used Xenopus laevis to investigate the process of testis cord development. Morphological observations revealed the presence of segmental gonomeres consisting of medullary knots in male gonads at stages 52-53, with no distinct gonomeres in female gonads. Further observations showed that cell proliferation occurs at specific sites along the anterior-posterior axis of the future testis at stage 50, which contributes to the formation of medullary knots. At stage 53, adjacent gonomeres become close to each other, resulting in fusion; then (pre-)Sertoli cells aggregate and form primitive testis cords, which ultimately become testis cords when germ cells are present inside. The process of testis cord formation in X. laevis appears to be more complex than in amniotes. Strikingly, steroidogenic cells appear earlier than (pre-)Sertoli cells in differentiating testes of X. laevis, which differs from earlier differentiation of (pre-)Sertoli cells in amniotes. Importantly, we found that the mesonephros is connected to the testis gonomere at a specific site at early larval stages and that these connections become efferent ducts after metamorphosis, which challenges the previous concept that the mesonephric side and the gonadal side initially develop in isolation and then connect to each other in amphibians and amniotes. |
| WOS研究方向 | Developmental Biology |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/45702]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, 18 Shuangqing Rd, Beijing 100085, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Yuanyuan,Li, Jinbo,Cai, Man,et al. Development of Testis Cords and the Formation of Efferent Ducts in Xenopus laevis: Differences and Similarities with Other Vertebrates[J]. SEXUAL DEVELOPMENT,2021,14(1-6):66-79. |
| APA | Li, Yuanyuan,Li, Jinbo,Cai, Man,&Qin, Zhanfen.(2021).Development of Testis Cords and the Formation of Efferent Ducts in Xenopus laevis: Differences and Similarities with Other Vertebrates.SEXUAL DEVELOPMENT,14(1-6),66-79. |
| MLA | Li, Yuanyuan,et al."Development of Testis Cords and the Formation of Efferent Ducts in Xenopus laevis: Differences and Similarities with Other Vertebrates".SEXUAL DEVELOPMENT 14.1-6(2021):66-79. |
入库方式： OAI收割
来源：生态环境研究中心
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