Stereoselective Total Synthesis of Siladenoserinols A and D
文献类型：期刊论文
| 作者 | Liu, Yinxin; Liu, Jun; Zhao, Chuanfang; Du, Yuguo |
| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2021-05-07 |
| 卷号 | 23期号:9页码:3264-3268 |
| ISSN号 | 1523-7060 |
| 英文摘要 | The stereoselective total synthesis of siladenoserinols A and D has been accomplished using carbohydrate as a chiral template. The feature of this work is to build the medicinally privileged 6,8-DOBCO scaffold through a cascade reaction of hydrogenation/deacetalization/ketalization in a one-pot process, that is, to take advantage of a thermodynamically controlled bicyclization of polyhydroxyketone under HCl/MeOH reaction conditions. The current cost-effective synthetic strategy could facilitate the bioactivity investigation of siladenoserinols. |
| WOS研究方向 | Chemistry, Organic |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/45845]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 作者单位 | 1.Univ Chinese Acad Sci, Sch Chem Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China 3.Jiangxi Normal Univ, Natl Engn Res Ctr Carbohydrate Synth, Nanchang 330022, Jiangxi, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Yinxin,Liu, Jun,Zhao, Chuanfang,et al. Stereoselective Total Synthesis of Siladenoserinols A and D[J]. ORGANIC LETTERS,2021,23(9):3264-3268. |
| APA | Liu, Yinxin,Liu, Jun,Zhao, Chuanfang,&Du, Yuguo.(2021).Stereoselective Total Synthesis of Siladenoserinols A and D.ORGANIC LETTERS,23(9),3264-3268. |
| MLA | Liu, Yinxin,et al."Stereoselective Total Synthesis of Siladenoserinols A and D".ORGANIC LETTERS 23.9(2021):3264-3268. |
入库方式： OAI收割
来源：生态环境研究中心
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