Nucleophilic and redox properties of polybrominated diphenyl ether derived-quinone/hydroquinone metabolites are responsible for their neurotoxicity
文献类型：期刊论文
| 作者 | Xu, Lei; Wang, Yuting; Song, Erqun; Song, Yang |
| 刊名 | JOURNAL OF HAZARDOUS MATERIALS
 |
| 出版日期 | 2021-12-15 |
| 卷号 | 136页码:122-131 |
| 关键词 | Zero valent iron Anaerobic digestion Antibiotic resistance genes High-throughput qPCR Swine manure |
| ISSN号 | 0956-053X |
| 英文摘要 | It is unadvisable to discuss the antibiotic resistance genes (ARGs) reduction in anaerobic digestion (AD) system neglecting its main purpose-methane production. The methane production improvement coupling with antibiotic resistance genes (ARGs) reduction in anaerobic digestion (AD) by zero valent iron (ZVI) were simultaneously investigated. Whether the role of ZVI on the ARGs fate was random or specific was clarified through the highthroughput qPCR (HT-qPCR). Results indicated that ZVI improved methane production and ARGs reduction by 23.9% and 25.0%, respectively. The improved methane production was associated with chemical reaction and variances of microbial community caused by ZVI, where DIET between Petrimonas, Clostridium and Syntrophomonas, Methanosarcina was established along with ACAS being enriched. ZVI specifically, not randomly, facilitated the reduction of aminoglycoside resistance genes of antibiotic inactivation and tetracycline resistance genes of ribosomal protection proteins. The specifical reduction could be attributed to enzyme activity inhibition and intracellular ionic disturbance caused by higher amounts of ZVI, although most of ARGs fate could be well explained by microbial community which contributed the most to ARGs dynamics as a whole. ZVI-based AD was a promising way for the improvement of methane production coupling ARGs reduction. |
| 源URL | [https://ir.rcees.ac.cn/handle/311016/46817]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 作者单位 | 1.Southwest Univ, Coll Pharmaceut Sci, Key Lab Luminescence Anal & Mol Sensing, Minist Educ, 2 Tiansheng Rd, Chongqing 400715, Peoples R China 2.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, 18 Shuangqing Rd, Beijing 100085, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Lei,Wang, Yuting,Song, Erqun,et al. Nucleophilic and redox properties of polybrominated diphenyl ether derived-quinone/hydroquinone metabolites are responsible for their neurotoxicity[J]. JOURNAL OF HAZARDOUS MATERIALS,2021,136:122-131. |
| APA | Xu, Lei,Wang, Yuting,Song, Erqun,&Song, Yang.(2021).Nucleophilic and redox properties of polybrominated diphenyl ether derived-quinone/hydroquinone metabolites are responsible for their neurotoxicity.JOURNAL OF HAZARDOUS MATERIALS,136,122-131. |
| MLA | Xu, Lei,et al."Nucleophilic and redox properties of polybrominated diphenyl ether derived-quinone/hydroquinone metabolites are responsible for their neurotoxicity".JOURNAL OF HAZARDOUS MATERIALS 136(2021):122-131. |
入库方式： OAI收割
来源：生态环境研究中心
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