Indoor exposure to selected flame retardants and quantifying importance of environmental, human behavioral and physiological parameters
文献类型：期刊论文
| 作者 | Li, Zengwei; Zhang, Xianming; Wang, Bin; Shen, Guofeng; Zhang, Qinghua; Zhu, Ying
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| 刊名 | SCIENCE OF THE TOTAL ENVIRONMENT
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| 出版日期 | 2022-08-20 |
| 卷号 | 835期号:0页码:155422 |
| ISSN号 | 0048-9697 |
| 关键词 | POLYBROMINATED DIPHENYL ETHERS SEMIVOLATILE ORGANIC-COMPOUNDS MASS-TRANSFER HOUSE-DUST HAND WIPES MIGRATION PATHWAYS TEST CHAMBER ORGANOPHOSPHATE EMISSIONS ASSOCIATIONS |
| 英文摘要 | vIndoor exposure to organic flame retardants (FRs) has raised extensive concern due to associated adverse health effects. Indoor-exposure induced daily intakes of six widely used FRs individually ranged 0.002-611 ng/day and 0.02-463 ng/day, respectively, for adults and 2-6-year-old children; and resulting internal exposure levels ranged 0.1-159 and 2.1-4500 ng/g lipid, respectively. A proportion of 0.001-5.9% and 0.006-10.3% of individual FRs emitted into indoor air ultimately entered bodies of adults and children respectively. Tris(2-chloroisopropyl)phosphate dominated in emissions, whilst 2-ethylhexyl-2,3,4,5-tetrabromobenzoate dominated in human bodies. Hand-tomouth contact was the most important exposure pathway for less volatile FRs including most brominated FRs, whilst inhalation was the predominant intake pathway of tris(2-chloroisopropyl)phosphate. Relative importance of 29 environmental, behavioral and physiological parameters was ranked to explore key drivers influencing exposure and accumulation of FRs in humans. Results suggested that frequent bathing and handwashing can reduce exposure effectively, especially for children. Bodyweight and lipid fraction were only positively related to internal accumulation and body-weight-normalized concentrations of compounds with low metabolic rates (half-lives >= 103 h) in humans. Our findings help control indoor exposure to FRs and are supportive of human exposome studies in the future. |
| 源URL | [https://ir.rcees.ac.cn/handle/311016/47554]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 通讯作者 | Zhu, Ying |
| 作者单位 | 1.Peking Univ, Sch Publ Hlth, Dept Epidemiol & Biostat, Beijing 100191, Peoples R China 2.Concordia Univ, Dept Chem & Biochem, 7141 Sherbrooke St West, Montreal, PQ H4B 1R6, Canada 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China 5.Peking Univ, Coll Urban & Environm Sci, Lab Earth Surface Proc, Beijing 100871, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Zengwei,Zhang, Xianming,Wang, Bin,et al. Indoor exposure to selected flame retardants and quantifying importance of environmental, human behavioral and physiological parameters[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2022,835(0):155422. |
| APA | Li, Zengwei,Zhang, Xianming,Wang, Bin,Shen, Guofeng,Zhang, Qinghua,&Zhu, Ying.(2022).Indoor exposure to selected flame retardants and quantifying importance of environmental, human behavioral and physiological parameters.SCIENCE OF THE TOTAL ENVIRONMENT,835(0),155422. |
| MLA | Li, Zengwei,et al."Indoor exposure to selected flame retardants and quantifying importance of environmental, human behavioral and physiological parameters".SCIENCE OF THE TOTAL ENVIRONMENT 835.0(2022):155422. |
入库方式： OAI收割
来源：生态环境研究中心
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