Passive Smoking Exposure Modifies Cardiovascular Structure and Function: Beijing Child Growth and Health Cohort (PROC) Study
文献类型：期刊论文
| 作者 | Xiao, Huidi; Li, Menglong; Li, Aijing ; Amaerjiang, Nubiya; Zunong, Jiawulan; Vermund, Sten H.; Perez-Escamilla, Rafael; Song, Maoyong; Hu, Yifei; Jiang, Guibin
|
| 刊名 | ENVIRONMENTAL SCIENCE & TECHNOLOGY
 |
| 出版日期 | 2022-09-15 |
| 期号 | 0页码:1-9 |
| ISSN号 | 0013-936X |
| 关键词 | SECONDHAND SMOKE PARENTAL SMOKING ATRIAL-FIBRILLATION RISK ASSOCIATION ADULTHOOD DISEASE HYPERTENSION ADOLESCENTS PREVALENCE |
| 英文摘要 | Passive smoking exposure in children is prevalent worldwide and exposes children to respiratory and systemic toxins. In this study, we enrolled 568 children to study how secondhand smoke (SHS) might affect children's cardiovascular health in China. The measurement of nicotine and its metabolites in urine showed that 78.9% of children were exposed to SHS. Children exposed to SHS had greater interventricular septum thickness (p = 0.005) and left ventricular mass index (p = 0.008) than nonexposed children. Urinary norcotinine levels were associated with increased ascending aorta diameter (beta = 0.10, 95%CI 0.02-0.17) and decreased left ventricular end systolic diameter (beta = -0.10, 95%CI -0.19 to - 0.01). The effects of SHS exposure on cardiovascular function: norcotinine levels associated with lower left ventricular mass index (beta = -0.32, 95%CI -0.59 to -0.05), left ventricular end diastolic volume index (beta = -0.43, 95%CI -0.85 to -0.02), and left ventricular end systolic volume index (beta = -0.20, 95%CI -0.37 to - 0.03). Moreover, there no no significant associations of nicotine, cotinine, and trans-3 '-hydroxycotinine with cardiovascular health. Overall, SHS exposure in children remains prevalent in Beijing and may affect children's cardiovascular development, in both structure and function. It suggests that stricter and practical measures are needed toward the elimination of tobacco use in children's environments. |
| 源URL | [https://ir.rcees.ac.cn/handle/311016/47598]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 作者单位 | 1.Capital Med Univ, Sch Publ Hlth, Beijing Key Lab Environm Toxicol, Beijing 100069, Peoples R Ch 2.Yale Univ, Yale Sch Publ Hlth, New Haven, CT 06510 USA 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Chem & Ecotoxicol, Beijing 100085, Peoples R China 5.Capital Med Univ, Sch Publ Hlth, Dept Child Adolescent Hlth & Maternal Care, Beijing 100069, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xiao, Huidi,Li, Menglong,Li, Aijing,et al. Passive Smoking Exposure Modifies Cardiovascular Structure and Function: Beijing Child Growth and Health Cohort (PROC) Study[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY,2022(0):1-9. |
| APA | Xiao, Huidi.,Li, Menglong.,Li, Aijing.,Amaerjiang, Nubiya.,Zunong, Jiawulan.,...&Jiang, Guibin.(2022).Passive Smoking Exposure Modifies Cardiovascular Structure and Function: Beijing Child Growth and Health Cohort (PROC) Study.ENVIRONMENTAL SCIENCE & TECHNOLOGY(0),1-9. |
| MLA | Xiao, Huidi,et al."Passive Smoking Exposure Modifies Cardiovascular Structure and Function: Beijing Child Growth and Health Cohort (PROC) Study".ENVIRONMENTAL SCIENCE & TECHNOLOGY .0(2022):1-9. |
入库方式： OAI收割
来源：生态环境研究中心
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。