Aging Processes Dramatically Alter the Protein Corona Constitution, Cellular Internalization, and Cytotoxicity of Polystyrene Nanoplastics
文献类型：期刊论文
| 作者 | Wen, Jing; Sun, Hang; Liu, Zixuan; Zhu, Xiangyu ; Qin, Zongming; Song, Erqun; Song, Yang
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| 刊名 | ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
 |
| 出版日期 | 2022 |
| 卷号 | 9期号:11页码:1-7 |
| 关键词 | nanoplastics microplastics aging weathering corona |
| ISSN号 | 2328-8930 |
| 英文摘要 | Humans are exposed to nanoplastics (NPs) through different routes, which raises critical concerns of related health effects. Due to their small sizes, NPs are accessible to the bloodstream and prone to interact with plasma proteins. NPs are susceptible to different aging processes before entering the human body, and it is plausible to evaluate the effect of aging on the physicochemical and biological properties of NPs. Here, we found that ultraviolet (UV) and ozone (O3) aging treatments caused the oxidation of polystyrene NPs, resulting in their differential adsorption characteristics toward plasma proteins. More impor-tantly, UV and O3 aging led to reduced cellular internalization of NPs and herein relieved their cytotoxic effect. Together, our current finding further enriches the understanding of NPs' toxicity in a realistic scenario. |
| 源URL | [https://ir.rcees.ac.cn/handle/311016/48474]  |
| 专题 | 生态环境研究中心_环境化学与生态毒理学国家重点实验室 |
| 作者单位 | 1.Chinese Academy of Sciences 2.Research Center for Eco-Environmental Sciences (RCEES) 3.Southwest University - China |
| 推荐引用方式 GB/T 7714 | Wen, Jing,Sun, Hang,Liu, Zixuan,et al. Aging Processes Dramatically Alter the Protein Corona Constitution, Cellular Internalization, and Cytotoxicity of Polystyrene Nanoplastics[J]. ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS,2022,9(11):1-7. |
| APA | Wen, Jing.,Sun, Hang.,Liu, Zixuan.,Zhu, Xiangyu.,Qin, Zongming.,...&Song, Yang.(2022).Aging Processes Dramatically Alter the Protein Corona Constitution, Cellular Internalization, and Cytotoxicity of Polystyrene Nanoplastics.ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS,9(11),1-7. |
| MLA | Wen, Jing,et al."Aging Processes Dramatically Alter the Protein Corona Constitution, Cellular Internalization, and Cytotoxicity of Polystyrene Nanoplastics".ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS 9.11(2022):1-7. |
入库方式： OAI收割
来源：生态环境研究中心
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