Advances in Magnetic Nanoparticle-Driven Delivery of Gene Therapies towards Prostate Cancer
文献类型：期刊论文
| 作者 | Panday, Raju; Abdalla, Ahmed M. E.; Neupane, Manisha; Khadka, Sujan; Kricha, Aymane; Yang, Guang |
| 刊名 | JOURNAL OF NANOMATERIALS
 |
| 出版日期 | 2021-09-15 |
| 卷号 | 2021页码:- |
| ISSN号 | 1687-4110 |
| 英文摘要 | Conventional treatment possibilities for one of the most common diseases among men, i.e., prostate cancer has several side effects. Gene-based therapy such as siRNA, CRISPR/Cas9, pDNA, and miRNA have emerged as an alternative, combating posttherapy side effects and drug resistance. Magnetic nanoparticles have been appropriately modified and functionalized to efficiently deliver the gene therapy-based active compounds to prostate tumor cells. The main purpose of this review article is to highlight the strategies currently being utilized for the treatment of prostate cancer using magnetic nanoparticles for delivery of genetic material using both the passive and active (ligand-based) targeting. It further discusses the challenges in efficient delivery of therapeutics to tumor sites and their remedial approaches. Finally, it provides a glimpse of future advances for tumor-specific modifications of magnetic nanoparticles to combat prostate cancer. |
| WOS研究方向 | Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/45903]  |
| 专题 | 生态环境研究中心_环境水质学国家重点实验室 |
| 作者单位 | 1.Univ Bahri, Coll Appl Sci, Dept Biochem, Khartoum 166011111, Sudan 2.Natl Inst Sci & Technol, Dept Biotechnol, Kathmandu 44600, Nepal 3.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Environm Aquat Chem, Beijing 100085, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.Huazhong Univ Sci & Technol, Dept Biomed Engn, Coll Life Sci & Technol, Wuhan 430074, Peoples R China |
| 推荐引用方式 GB/T 7714 | Panday, Raju,Abdalla, Ahmed M. E.,Neupane, Manisha,et al. Advances in Magnetic Nanoparticle-Driven Delivery of Gene Therapies towards Prostate Cancer[J]. JOURNAL OF NANOMATERIALS,2021,2021:-. |
| APA | Panday, Raju,Abdalla, Ahmed M. E.,Neupane, Manisha,Khadka, Sujan,Kricha, Aymane,&Yang, Guang.(2021).Advances in Magnetic Nanoparticle-Driven Delivery of Gene Therapies towards Prostate Cancer.JOURNAL OF NANOMATERIALS,2021,-. |
| MLA | Panday, Raju,et al."Advances in Magnetic Nanoparticle-Driven Delivery of Gene Therapies towards Prostate Cancer".JOURNAL OF NANOMATERIALS 2021(2021):-. |
入库方式： OAI收割
来源：生态环境研究中心
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