Sample preparation methods for the analysis of microplastics in freshwater ecosystems: a review
文献类型：期刊论文
| 作者 | Razeghi, Nastaran; Hamidian, Amir Hossein; Mirzajani, Alireza; Abbasi, Sajjad; Wu, Chenxi; Zhang, Yu ; Yang, Min
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| 刊名 | ENVIRONMENTAL CHEMISTRY LETTERS
 |
| 出版日期 | 2021 |
| 卷号 | 287页码:- |
| 关键词 | Pyrethroids Metabolite Thyroid hormones Histopathology Gene expression |
| ISSN号 | 0269-7491 |
| 英文摘要 | Although the thyroid effects of pyrethroids on non-target organisms have been well studied, research on the toxic effects of pyrethorid metabolites is still limited. In this study, a type of representative Chinese lizards was used as the model and exposed to environmentally relevant concentrations of lambda-cyhalothrin (LCT) and 3-phenoxybenzoic acid (PBA) through cultivation on 3 and 15 mu g/g soil to evaluate and compare their disruption effects on lizard hypothalamus-pituitary-thyroid (HPT) axis. The alterations occurred in lizards were examined through histopathology analyses, hormone level and gene expression measurements, the molecular binding interactions were analyzed in silico as well. The results showed that LCT exposure increased the plasma triiodothyronine (T3), thyroxine (T4) levels and the follicular epithelium heights of thyroid glands, whereas PBA induced no or much less degree of alterations. The ugt and dio2 gene expression in lizard liver was significantly up-regulated by LCT, but PBA caused less or opposite effects. The in silico homology simulation illustrated that LCT binds to TR alpha in the similar way of T3, while PBA binds to TRH in the same manner of T3. The results demonstrated that both LCT and its metabolite-PBA could disrupt lizard HPT axis but through distinct mechanisms. The information would facilitate the comprehensive environmental safety assessment of pyrethroids. |
| 源URL | [https://ir.rcees.ac.cn/handle/311016/46863]  |
| 专题 | 生态环境研究中心_环境水质学国家重点实验室 |
| 作者单位 | 1.Shiraz Univ, Coll Sci, Dept Earth Sci, Shiraz 71454, Iran 2.Marie Curie Sklodowska Univ, Fac Chem, Dept Radiochemistry & Environm Chem, PL-20031 Lublin, Poland 3.[Wu, Chenxi 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 5.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China 6.Univ Tehran, Fac Nat Resources, Dept Environm Sci & Engn, P.O. Box 4314, Karaj 3158777878, Iran 7.Chinese Acad Sci, Res Ctr EcoEnvironmental Sci, State Key Lab Environm Aquat Chem, Beijing 100085, Peoples R China 8.Agr Res Educ & Extens Org AREEO, Inland Waters Aquaculture Res Ctr, Iranian Fisher Sci Res Inst, P.O. Box 66, Bandare Anzali, Iran |
| 推荐引用方式 GB/T 7714 | Razeghi, Nastaran,Hamidian, Amir Hossein,Mirzajani, Alireza,et al. Sample preparation methods for the analysis of microplastics in freshwater ecosystems: a review[J]. ENVIRONMENTAL CHEMISTRY LETTERS,2021,287:-. |
| APA | Razeghi, Nastaran.,Hamidian, Amir Hossein.,Mirzajani, Alireza.,Abbasi, Sajjad.,Wu, Chenxi.,...&Yang, Min.(2021).Sample preparation methods for the analysis of microplastics in freshwater ecosystems: a review.ENVIRONMENTAL CHEMISTRY LETTERS,287,-. |
| MLA | Razeghi, Nastaran,et al."Sample preparation methods for the analysis of microplastics in freshwater ecosystems: a review".ENVIRONMENTAL CHEMISTRY LETTERS 287(2021):-. |
入库方式： OAI收割
来源：生态环境研究中心
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