Bioactive Effects of Curcumin in Human Immunodeficiency Virus Infection Along with the Most Effective Isolation Techniques and Type of Nanoformulations
文献类型：期刊论文
| 作者 | Butnariu, Monica; Quispe, Cristina; Koirala, Niranjan; Khadka, Sujan; Salgado-Castillo, Carla Marina; Akram, Muhammad; Anum, Rabia; Yeskaliyeva, Balakyz; Cruz-Martins, Natalia; Martorell, Miquel |
| 刊名 | INTERNATIONAL JOURNAL OF NANOMEDICINE
 |
| 出版日期 | 2022-01 |
| 卷号 | 17期号:0页码:3619-3632 |
| 关键词 | MICROWAVE-ASSISTED EXTRACTION ANTIRETROVIRAL THERAPY BIOLOGICAL-ACTIVITIES HIV-1 INTEGRASE BREAST-CANCER UP-REGULATION NANOPARTICLES DERIVATIVES MECHANISMS INHIBITION |
| ISSN号 | 1178-2013 |
| 英文摘要 | Human immunodeficiency virus (HIV) is one of the leading causes of death worldwide, with African countries being the worst affected by this deadly virus. Curcumin (CUR) is a Curcuma longa-derived polyphenol that has attracted the attention of researchers due to its antimicrobial, anti-inflammatory, antioxidant, immunomodulatory and antiviral effects. CUR also demonstrates anti-HIV effects by acting as a possible inhibitor of gp120 binding, integrase, protease, and topoisomerase II activities, besides also exerting a protective action against HIV-associated diseases. However, its effectiveness is limited due to its poor water solubility, rapid metabolism, and systemic elimination. Nanoformulations have been shown to be useful to enhance curcumin's bioavailability and its effectiveness as an anti-HIV agent. In this sense, bioactive effects of CUR in HIV infection are carefully reviewed, along with the most effective isolation techniques and type of nanoformulations available. |
| 源URL | [https://ir.rcees.ac.cn/handle/311016/47676]  |
| 专题 | 生态环境研究中心_环境水质学国家重点实验室 |
| 通讯作者 | Cruz-Martins, Natalia |
| 作者单位 | 1.Univ Life Sci King Mihai I Timisoara, Chem & Biochem Discipline, Calea Aradului 119, Timis 300645, Romania 2.Univ Macau, Fac Sci & Technol, Lab Biotechnol, Macau 999078, Peoples R China 3.Dr Koirala Res Inst Biotechnol & Biodivers, Dept Nat Prod Res, Kathmandu 44600, Nepal 4.Univ Arturo Prat, Fac Ciencias Salud, Iquique 1110939, Chile 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Butnariu, Monica,Quispe, Cristina,Koirala, Niranjan,et al. Bioactive Effects of Curcumin in Human Immunodeficiency Virus Infection Along with the Most Effective Isolation Techniques and Type of Nanoformulations[J]. INTERNATIONAL JOURNAL OF NANOMEDICINE,2022,17(0):3619-3632. |
| APA | Butnariu, Monica.,Quispe, Cristina.,Koirala, Niranjan.,Khadka, Sujan.,Salgado-Castillo, Carla Marina.,...&Sharifi-Rad, Javad.(2022).Bioactive Effects of Curcumin in Human Immunodeficiency Virus Infection Along with the Most Effective Isolation Techniques and Type of Nanoformulations.INTERNATIONAL JOURNAL OF NANOMEDICINE,17(0),3619-3632. |
| MLA | Butnariu, Monica,et al."Bioactive Effects of Curcumin in Human Immunodeficiency Virus Infection Along with the Most Effective Isolation Techniques and Type of Nanoformulations".INTERNATIONAL JOURNAL OF NANOMEDICINE 17.0(2022):3619-3632. |
入库方式： OAI收割
来源：生态环境研究中心
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