Co-selection of antibiotic resistance genes, and mobile genetic elements in the presence of heavy metals in poultry farm environments
文献类型：期刊论文
| 作者 | Mazhar, Sohaib H.; Li, Xuanji; Rashid, Azhar; Su, JunMing; Xu, Junqiang; Brejnrod, Asker Daniel; Su, Jian-Qiang; Wu, Yijian; Zhu, Yong-Guan; Zhou, Shun Gui |
| 刊名 | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| 出版日期 | 2021-02-10 |
| 卷号 | 755页码:- |
| ISSN号 | 0048-9697 |
| 关键词 | Co-selection ARGs Horizontal gene transfer Heavy metals Integrase Transposons |
| 英文摘要 | Environmental selection of antibiotic resistance genes (ARGs) is considered to be caused by antibiotic or metal residues, frequently used in livestock. In this study we examined three commercial poultry farms to correlate the co-occurrence patterns of antibiotic and metal residues to the presence of ARGs. We quantified 283 ARGs, 12 mobile genetic elements (MGEs), 49 targeted antibiotics, 7 heavy metals and sequenced 16S rRNA genes. The abundance and type of ARG were significantly enriched in manure while soil harbored the most diverse bacterial community. Procrustes analysis displayed significant correlations between ARGs/MGEs and the microbiome. Cadmium (Cd), arsenic (As), zinc (Zn), copper (Cu) and lead (Pb) were responsible for a majority of positive correlations to ARGs when compared to antibiotics. Integrons and transposons co-occurred with ARGs corresponding to 9 classes of antibiotics, especially Class1 integrase intI-1LC. Redundancy analysis (RDA) and Variance partitioning analysis (VPA) showed that antibiotics, metals, MGEs and bacteria explain solely 0.7%, 5.7%, 12.4%, and 21.9% of variances of ARGs in the microbial community, respectively. These results suggested that bacterial composition and horizontal gene transfer were the major factors shaping the composition of ARGs; Metals had a bigger effect on ARG profile than detected antibiotics in this study. (C) 2020 Elsevier B.V. All rights reserved. |
| WOS研究方向 | Environmental Sciences |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/45443]  |
| 专题 | 生态环境研究中心_城市与区域生态国家重点实验室 |
| 作者单位 | 1.Fujian Agr & Forestry Univ, Coll Agr Resources & Environm, Inst Environm Microbiol, Fuzhou, Peoples R China 2.Univ Copenhagen, Sect Microbiol, Copenhagen, Denmark 3.Nucl Inst Food & Agr PAEC, Peshawar 25000, Pakistan 4.Univ Calif San Diego, Skaggs Sch Pharm, La Jolla, CA 92093 USA 5.Chinese Acad Sci, Inst Urban Environm, Key Lab Urban Environm & Hlth, 1799 Jimei Rd, Xiamen 361021, Peoples R China 6.Fujian Agr & Forestry Univ, Coll Anim Sci, Fuzhou 350002, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mazhar, Sohaib H.,Li, Xuanji,Rashid, Azhar,et al. Co-selection of antibiotic resistance genes, and mobile genetic elements in the presence of heavy metals in poultry farm environments[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2021,755:-. |
| APA | Mazhar, Sohaib H..,Li, Xuanji.,Rashid, Azhar.,Su, JunMing.,Xu, Junqiang.,...&Rensing, Christopher.(2021).Co-selection of antibiotic resistance genes, and mobile genetic elements in the presence of heavy metals in poultry farm environments.SCIENCE OF THE TOTAL ENVIRONMENT,755,-. |
| MLA | Mazhar, Sohaib H.,et al."Co-selection of antibiotic resistance genes, and mobile genetic elements in the presence of heavy metals in poultry farm environments".SCIENCE OF THE TOTAL ENVIRONMENT 755(2021):-. |
入库方式： OAI收割
来源：生态环境研究中心
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