Insights into the roles of fungi and protist in the giant panda gut microbiome and antibiotic resistome
文献类型：期刊论文
| 作者 | Zhu, Dong; Lu, Lu; Zhang, Zejun; Qi, Dunwu; Zhang, Mingchun; O'Connor, Patrick; Wei, Fuwen; Zhu, Yong-Guan |
| 刊名 | ENVIRONMENT INTERNATIONAL
 |
| 出版日期 | 2021 |
| 卷号 | 155页码:- |
| 关键词 | Fungi Protist Antibiotic resistance genes Network analysis Multitrophic communities Neutral model |
| ISSN号 | 0160-4120 |
| 英文摘要 | The mammal gut is a rich reservoir of antibiotic resistance genes (ARGs), and the relationship between bacterial communities and ARGs has been widely studied. Despite ecological significance of microeukaryotes (fungi and protists), our understanding of their roles in the mammal gut microbiome and antibiotic resistome is still limited. Here, we used amplicon sequencing, metagenomic sequencing and high-throughput quantitative PCR to examine microbiomes and antibiotic resistomes of 41 giant panda fecal samples from individuals with different genders, ages, sampling sites and diet. Our results show that diverse protists inhabit in the giant panda gut ecosystem, dominated by consumers. Higher abundance of protistan consumers was detected in the elder compared to subadult and adult giant pandas. Diet is the main driving factor of variation in ARGs in the giant panda gut microbiome. Weighted correlation network analysis identified two key microbial modules from multitrophic communities, which all contributed to the variation in ARGs in the giant panda gut. Protists occupied an important position in the two modules which were dominated by fungal taxa. Deterministic processes made a more important contribution to microbial community assembly of the two modules than to bacterial, fungal and protistan communities. This study sheds new light on how key microbial modules contribute to the variation in ARGs, which is crucial in understanding dynamics of antibiotic resistome in the mammal gut, particularly endangered species. |
| WOS研究方向 | Environmental Sciences |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/45493]  |
| 专题 | 生态环境研究中心_城市与区域生态国家重点实验室 |
| 作者单位 | 1.Chengdu Res Base Giant Panda Breeding, Chengdu 611081, Sichuan, Peoples R China 2.China West Normal Univ, Coll Environm Sci & Engn, Nanchong 637009, Peoples R China 3.Univ Adelaide, Ctr Global Food & Resources, Adelaide, SA 5005, Australia 4.China Conservat & Res Ctr Giant Panda, Dujiangyan 611830, Peoples R China 5.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, State Key Lab Urban & Reg Ecol, Beijing 100085, Peoples R China 6.China West Normal Univ, Coll Life Sci, Key Lab Southwest China Wildlife Resources Conser, Nanchong 637002, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Dong,Lu, Lu,Zhang, Zejun,et al. Insights into the roles of fungi and protist in the giant panda gut microbiome and antibiotic resistome[J]. ENVIRONMENT INTERNATIONAL,2021,155:-. |
| APA | Zhu, Dong.,Lu, Lu.,Zhang, Zejun.,Qi, Dunwu.,Zhang, Mingchun.,...&Zhu, Yong-Guan.(2021).Insights into the roles of fungi and protist in the giant panda gut microbiome and antibiotic resistome.ENVIRONMENT INTERNATIONAL,155,-. |
| MLA | Zhu, Dong,et al."Insights into the roles of fungi and protist in the giant panda gut microbiome and antibiotic resistome".ENVIRONMENT INTERNATIONAL 155(2021):-. |
入库方式： OAI收割
来源：生态环境研究中心
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