Neighbours matter: Effects of genomic organization on gene expression plasticity in response to environmental stresses during biological invasions
文献类型：期刊论文
| 作者 | Chen, Zaohuang; Huang, Xuena ; Fu, Ruiying; Zhan, Aibin
|
| 刊名 | COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS
 |
| 出版日期 | 2022-06 |
| 卷号 | 42期号:0页码:100992 |
| 关键词 | CAENORHABDITIS-ELEGANS PHENOTYPIC PLASTICITY CHANGING ENVIRONMENTS OPERONS EVOLUTION CLUSTERS COEXPRESSION ARCHITECTURE RECOVERY ORDER |
| ISSN号 | 1744-117X |
| 英文摘要 | Gene expression regulation has been widely recognized as an important molecular mechanism underlying phenotypic plasticity in environmental adaptation. However, it remains largely unexplored on the effects of genomic organization on gene expression plasticity under environmental stresses during biological invasions. Here, we use an invasive model ascidian, Ciona robusta, to investigate how genomic organization affects gene expression in response to salinity stresses during range expansions. Our study showed that neighboring genes were co-expressed and approximately 30% of stress responsive genes were physically clustered on chromosomes. Such coordinated expression was substantially affected by the physical distance and orientation of genes. Interestingly, the overall expression correlation of neighboring genes was significantly decreased under high salinity stresses, illustrating that the co-expression regulation could be disrupted by salinity challenges. Furthermore, the clustering of genes was associated with their function constraints and expression patterns operon genes enriched in gene expression machinery had the highest transcriptional activity and expression stability. Notably, our analyses showed that the tail-to-tail genes, mainly involved in biological functions related to phosphorylation, homeostatic process, and ion transport, exhibited higher intrinsic expression variability and greater response to salinity challenges. Altogether, the results obtained here provide new insights into the effects of gene organization on gene expression plasticity under environmental challenges, hence improving our knowledge on mechanisms of rapid environmental adaptation during biological invasions. |
| 源URL | [https://ir.rcees.ac.cn/handle/311016/47805]  |
| 专题 | 生态环境研究中心_中国科学院环境生物技术重点实验室 |
| 通讯作者 | Zhan, Aibin |
| 作者单位 | 1.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, 18 Shuangqing Rd,Haidian Dist, Beijing 100085, Peoples R China 2.Univ Chinese Acad Sci, 19A Yuquan Rd,Shijingshan Dist, Beijing 100049, Peoples R China 3.Chinese Acad Sci, 19A Yuquan Rd,Shijingshan Dist, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chen, Zaohuang,Huang, Xuena,Fu, Ruiying,et al. Neighbours matter: Effects of genomic organization on gene expression plasticity in response to environmental stresses during biological invasions[J]. COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS,2022,42(0):100992. |
| APA | Chen, Zaohuang,Huang, Xuena,Fu, Ruiying,&Zhan, Aibin.(2022).Neighbours matter: Effects of genomic organization on gene expression plasticity in response to environmental stresses during biological invasions.COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS,42(0),100992. |
| MLA | Chen, Zaohuang,et al."Neighbours matter: Effects of genomic organization on gene expression plasticity in response to environmental stresses during biological invasions".COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY D-GENOMICS & PROTEOMICS 42.0(2022):100992. |
入库方式： OAI收割
来源：生态环境研究中心
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