Microkinetic study of NO oxidation, standard and fast NH3-SCR on CeWOx at low temperatures
文献类型：期刊论文
| 作者 | Liu, Kuo; He, Hong ; Chu, Biwu
|
| 刊名 | CHEMICAL ENGINEERING JOURNAL
 |
| 出版日期 | 2021-11-01 |
| 卷号 | 156页码:- |
| 关键词 | Per-and polyfluoroalkyl substances Type 2 diabetes Fasting plasma glucose Hemoglobin A1c Lipid fractions |
| ISSN号 | 0160-4120 |
| 英文摘要 | Associations between per- and polyfluoroalkyl substances (PFASs) and the incidence of type 2 diabetes are controversial in epidemiological studies. In addition, limited data are available for assessing the health effects of novel PFAS alternatives. Our study evaluated the effects of PFAS exposure on type 2 diabetes by estimating the associations of PFASs in human serum with the risk of type 2 diabetes and levels of glycemic biomarkers and lipid fractions. The case-control study consisted of 304 participants from Shandong Province, East China, half of which were diagnosed with type 2 diabetes. Logistic regression showed that most PFASs were inversely associated with the risk of type 2 diabetes after adjusting for age, sex, and body mass index. However, concentrations of perfluorooctanoic acid (PFOA) in the control group were positively associated with fasting plasma glucose levels (beta = 0.04, 95% confidence interval (CI): 0.0003, 0.08), which may promote the development of type 2 diabetes. Furthermore, each log-unit increase in the concentrations of perfluorononanoic acid (PFNA), perfluoroundecanoic acid (PFUnDA), and 6:2 chlorinated polyfluoroalkyl ether sulfonic acid (Cl-PFESA) were associated with a total cholesterol increase (i.e., 17.49% (95% CI: 0.93%, 34.90%), 17.49% (95% CI: 4.71%, 31.83%), and 17.49% (95% CI: 4.71%, 31.83%), respectively). Positive associations were also observed between PFNA, PFUnDA, perfluorooctane sulfonate (PFOS), and 6:2 Cl-PFESA and low-density lipoprotein cholesterol. However, no associations between PFASs and hemoglobin A1c, triglycerides, or high-density lipoprotein cholesterol reached statistical significance, nor associations between PFAS mixtures and outcomes of interest. In conclusion, the significant correlations between serum PFASs and glycemic biomarkers and lipid fractions indicated that PFAS exposure may be a potential diabetogenic factor. To the best of our knowledge, this is the first study to assess the associations between novel Cl-PFESAs and type 2 diabetes, although the inverse associations observed require clarification in future studies. |
| 源URL | [https://ir.rcees.ac.cn/handle/311016/46875]  |
| 专题 | 生态环境研究中心_水污染控制实验室 |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Inst Urban Environm, Ctr Excellence Reg Atmospher Environm, Xiamen 361021, Peoples R China 3.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, Editorial Off Journal Environm Sci, Beijing 100085, Peoples R China 4.Chinese Acad Sci, State Key Joint Lab Environm Simulat & Pollut Con, Res Ctr Ecoenvironm Sci, Beijing 100085, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Kuo,He, Hong,Chu, Biwu. Microkinetic study of NO oxidation, standard and fast NH3-SCR on CeWOx at low temperatures[J]. CHEMICAL ENGINEERING JOURNAL,2021,156:-. |
| APA | Liu, Kuo,He, Hong,&Chu, Biwu.(2021).Microkinetic study of NO oxidation, standard and fast NH3-SCR on CeWOx at low temperatures.CHEMICAL ENGINEERING JOURNAL,156,-. |
| MLA | Liu, Kuo,et al."Microkinetic study of NO oxidation, standard and fast NH3-SCR on CeWOx at low temperatures".CHEMICAL ENGINEERING JOURNAL 156(2021):-. |
入库方式： OAI收割
来源：生态环境研究中心
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