Antibiotic resistance genes on the Qinghai-Tibet Plateau above an elevation of 5,000 m
文献类型：期刊论文
| 作者 | Wang, Xiaomin; Han, Chang; Lan, Bangrui; Wang, Cheng; Zhu, Guibing |
| 刊名 | ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
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| 页码 | - |
| 关键词 | Antibiotic resistance genes Qinghai-Tibet Plateau Elevation 5 000 m Class 1 integron |
| ISSN号 | 0944-1344 |
| 英文摘要 | Antibiotic resistance genes (ARGs) widely occur in both anthropogenic and remote environments. Several studies have investigated the distribution of antibiotic resistance in natural environments. However, the occurrence and diversity of ARGs in remote environments at high elevations have not yet been well elucidated. Abundance, diversity, as well as influencing factors of ARGs in different ecosystems on the Qinghai-Tibet Plateau beyond elevation 5,000 m were explored, using high-throughput quantitative PCR. Totally, 197 ARGs and 12 mobile genetic elements (MGEs) were determined with abundances ranging from 3.75 x 10(6) to 2.39 x 10(7) and from 2.21 x 10(4) to 1.62 x 10(6) copies g(-1), respectively. Both the absolute and relative abundances of ARGs in farmland were lower than those in wetland and grassland. The diversity and dominant resistance mechanism of ARG profiles showed obvious differences among these ecosystems. Bacterial communities and MGEs significantly correlated with ARG profiles, while physico-chemical factors showed little impact. The high abundance and strong positive correlation between integron intI-1 and ARGs suggested a high potential horizontal ARG transfer. Based on the results, the Qinghai-Tibet Plateau can be regarded as a considerable ARG gene pool. This study provides insights into the provenance of ARGs at high elevations. |
| WOS研究方向 | Environmental Sciences |
| 源URL | [http://ir.rcees.ac.cn/handle/311016/46174]  |
| 专题 | 生态环境研究中心_中国科学院饮用水科学与技术重点实验室 |
| 作者单位 | 1.Sun Yat Sen Univ, Southern Marine Sci & Engn Guangdong Lab Zhuhai, South China Sea Inst, Guangzhou 510006, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Res Ctr Ecoenvironm Sci, Key Lab Drinking Water Sci & Technol, Beijing 100085, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Xiaomin,Han, Chang,Lan, Bangrui,et al. Antibiotic resistance genes on the Qinghai-Tibet Plateau above an elevation of 5,000 m[J]. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH:-. |
| APA | Wang, Xiaomin,Han, Chang,Lan, Bangrui,Wang, Cheng,&Zhu, Guibing. |
| MLA | Wang, Xiaomin,et al."Antibiotic resistance genes on the Qinghai-Tibet Plateau above an elevation of 5,000 m".ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH |
入库方式： OAI收割
来源：生态环境研究中心
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