Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis
文献类型：期刊论文
| 作者 | Yang, Kezhen; Wang, Hongzhe; Xue, Shan; Qu, Xiaoxiao; Zou, Junjie; Le, Jie
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| 刊名 | JOURNAL OF EXPERIMENTAL BOTANY
 |
| 出版日期 | 2014 |
| 卷号 | 65期号:9页码:2449-2461 |
| 关键词 | Arabidopsis cell cycle stomatal development symmetric division transcription factor |
| ISSN号 | 0022-0957 |
| DOI | 10.1093/jxb/eru139 |
| 文献子类 | Article |
| 英文摘要 | The Arabidopsis stoma is a specialized epidermal valve made up of a pair of guard cells around a pore whose aperture controls gas exchange between the shoot and atmosphere. Guard cells (GCs) are produced by a symmetric division of guard mother cells (GMCs). The R2R3-MYB transcription factor FOUR LIPS (FLP) and its paralogue MYB88 restrict the division of a GMC to one. Previously, the upstream regions of several core cell cycle genes were identified as the direct targets of FLP/MYB88, including the B-type cyclin-dependent kinase CDKB1;1 and A2-type cyclin CYCA2;3. Here we show that CDKA;1 is also an immediate direct target of FLP/MYB88 through the binding to cis-regulatory elements in the CDKA;1 promoter region. CDKA;1 activity is required not only for normal GMC divisions but also for the excessive cell overproliferation in flp myb88 mutant GMCs. The impaired defects of GMC division in cdkb1;1 1;2 mutants could be partially rescued by a stage-specific expression of CDKA;1. Although targeted overexpression of CDKA;1 does not affect stomatal development, ectopic expression of the D3-type cyclin CYCD3;2 induces GC subdivision, resulting in a stoma with 3-4 GCs instead of the normal two. Co-overexpression of CDKA;1 with CYCD3;2, but not with CYCA2;3, confers a synergistic effect with respect to GC subdivision. Thus, in addition to a role in stomatal formative asymmetric divisions at early developmental stages, CDKA;1 is needed in triggering GMC symmetric divisions at the late stage of stomatal development. However, timely down-regulation of CDKA;1-CYCD3 activity is required for restriction of GC proliferation. |
| 学科主题 | Plant Sciences |
| 出版地 | OXFORD |
| 电子版国际标准刊号 | 1460-2431 |
| WOS关键词 | ASYMMETRIC CELL DIVISIONS ; PLANT DEVELOPMENT ; 4 LIPS ; PROLIFERATION ; ENDOREDUPLICATION ; DIFFERENTIATION ; EXPRESSION ; GENES ; PERSPECTIVE ; TRANSITION |
| WOS研究方向 | Plant Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000337978800018 |
| 出版者 | OXFORD UNIV PRESS |
| 资助机构 | National Natural Science Foundation of China [30971652, 31271463, 31071198] ; Chinese Academy of Sciences [KSCX2-YW-N-073] |
| 源URL | [http://ir.ibcas.ac.cn/handle/2S10CLM1/27141]  |
| 专题 | 中科院植物分子生理学重点实验室 |
| 作者单位 | Chinese Acad Sci, Inst Bot, Key Lab Plant Mol Physiol, Beijing 100093, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Kezhen,Wang, Hongzhe,Xue, Shan,et al. Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis[J]. JOURNAL OF EXPERIMENTAL BOTANY,2014,65(9):2449-2461. |
| APA | Yang, Kezhen,Wang, Hongzhe,Xue, Shan,Qu, Xiaoxiao,Zou, Junjie,&Le, Jie.(2014).Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis.JOURNAL OF EXPERIMENTAL BOTANY,65(9),2449-2461. |
| MLA | Yang, Kezhen,et al."Requirement for A-type cyclin-dependent kinase and cyclins for the terminal division in the stomatal lineage of Arabidopsis".JOURNAL OF EXPERIMENTAL BOTANY 65.9(2014):2449-2461. |
入库方式： OAI收割
来源：植物研究所
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