Construction of Vinyl-Substituted N-Heterocycles via Rh(III)- Catalyzed C-H Functionalization/Annulation of Pyrazolidinones
文献类型:期刊论文
作者 | Zhang, Shurui2,3; Hu, Shulei1,4; Wang, Kean5; Yang, Zhao4; Liu, Hong1,3,4,5![]() ![]() |
刊名 | ADVANCED SYNTHESIS & CATALYSIS
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出版日期 | 2023-01-18 |
页码 | 7 |
关键词 | annulation reactions C-H activation pyrazolidinone Rh(III)-catalyzed |
ISSN号 | 1615-4150 |
DOI | 10.1002/adsc.202201065 |
通讯作者 | Yang, Zhao(yzcpu@163.com) ; Liu, Hong(hliu@simm.ac.cn) ; Wang, Jiang(jwang@lglab.ac.cn) |
英文摘要 | The transition-metal-catalyzed C-H activation and annulation reactions of pyrazolidinones with 4-vinyl-1,3-dioxolan-2-one or vinylene carbonate are described herein. This protocol provided two types of pyrazolo[1,2-a]cinnolines as essential assets for the development of bioactive compounds, and the synthetic practicality was performed and explained with 44 examples. The possible mechanism of these two reactions is proposed based on preliminary studies and previous reports, and no oxidant was added to both reactions. |
WOS关键词 | DIRECTING-GROUP ; CYCLOADDITIONS ; CINNOLINES ; ALKYNES ; ARENES |
资助项目 | National Natural Science Foundation of China[82130105] ; National Natural Science Foundation of China[82121005] ; National Natural Science Foundation of China[22177124] ; Lingang Laboratory[LG-GG-202204-02] |
WOS研究方向 | Chemistry |
语种 | 英语 |
WOS记录号 | WOS:000919009700001 |
出版者 | WILEY-V C H VERLAG GMBH |
源URL | [http://119.78.100.183/handle/2S10ELR8/303690] ![]() |
专题 | 新药研究国家重点实验室 |
通讯作者 | Yang, Zhao; Liu, Hong; Wang, Jiang |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China 2.Lingang Lab, Shanghai 200031, Peoples R China 3.ShanghaiTech Univ, Sch Life Sci & Technol, Shanghai 200031, Peoples R China 4.China Pharmaceut Univ, 639 Longmian Ave, Nanjing 211198, Peoples R China 5.Nanjing Univ Chinese Med, Sch Chinese Mat Med, Nanjing 210023, Peoples R China |
推荐引用方式 GB/T 7714 | Zhang, Shurui,Hu, Shulei,Wang, Kean,et al. Construction of Vinyl-Substituted N-Heterocycles via Rh(III)- Catalyzed C-H Functionalization/Annulation of Pyrazolidinones[J]. ADVANCED SYNTHESIS & CATALYSIS,2023:7. |
APA | Zhang, Shurui,Hu, Shulei,Wang, Kean,Yang, Zhao,Liu, Hong,&Wang, Jiang.(2023).Construction of Vinyl-Substituted N-Heterocycles via Rh(III)- Catalyzed C-H Functionalization/Annulation of Pyrazolidinones.ADVANCED SYNTHESIS & CATALYSIS,7. |
MLA | Zhang, Shurui,et al."Construction of Vinyl-Substituted N-Heterocycles via Rh(III)- Catalyzed C-H Functionalization/Annulation of Pyrazolidinones".ADVANCED SYNTHESIS & CATALYSIS (2023):7. |
入库方式: OAI收割
来源:上海药物研究所
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