Redox-neutral rhodium(iii)-catalyzed divergent synthesis of tetrasubstituted 1,3-enynes and alkynylated benzofurans
文献类型：期刊论文
| 作者 | Gong, Xin1; Yu, Na2; Gu, Linghui1; Li, Zheyu1; Ma, Wenbo1; Zhao, Fei1,3 |
| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
 |
| 出版日期 | 2023-01-07 |
| 卷号 | 21期号:1页码:147-152 |
| ISSN号 | 1477-0520 |
| DOI | 10.1039/d2ob01800d |
| 通讯作者 | Li, Zheyu() ; Ma, Wenbo(wenboma@hotmail.com) ; Zhao, Fei(zhaofei@cdu.edu.cn) |
| 英文摘要 | With the assistance of the acetamido directing group (DG), a rhodium-catalyzed C-H alkenylation/DG migration cascade for the synthesis of tetrasubstituted 1,3-enynes from N-phenoxyacetamides and 1,3-diynes has been achieved in this work. Alternatively, a rhodium-catalyzed [3 + 2] annulation for the synthesis of alkynylated benzofurans from the same set of substrates has also been achieved by simply changing the reaction conditions. This work highlights the tunable divergent synthesis of valuable compounds triggered by C-H activation. |
| WOS关键词 | C-H FUNCTIONALIZATION ; N-PHENOXYACETAMIDES ; BOND ACTIVATION ; DIRECTING-GROUP ; FACILE CONSTRUCTION ; ALKYNES ; ALKENES ; OLEFINATION ; STRATEGY ; INDOLES |
| 资助项目 | Key Research and Development Program of Ningxia Province[2022CMG03143] ; State Key Laboratory of Drug Research[SIMM2105KF-09] ; National Natural Science Foundation of China[21602022] ; Chengdu Talents Program ; 1000 Talents Program of Sichuan Province ; Longquanyi District Talents Program ; Science and Technology Program of Sichuan Province[2018JY0345] ; Chengdu University New Faculty Start-up Funding[2081915037] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:000900469400001 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/303908]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Li, Zheyu; Ma, Wenbo; Zhao, Fei |
| 作者单位 | 1.Chengdu Univ, Sichuan Ind Inst Antibiot, Sch Pharm, Antibiot Res & Reevaluat Key Lab Sichuan Prov, Chengdu 610106, Peoples R China 2.Ningxia Med Univ, Dept Preparat Ctr, Gen Hosp, Yinchuan 750004, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zu Chong Zhi Rd, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gong, Xin,Yu, Na,Gu, Linghui,et al. Redox-neutral rhodium(iii)-catalyzed divergent synthesis of tetrasubstituted 1,3-enynes and alkynylated benzofurans[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2023,21(1):147-152. |
| APA | Gong, Xin,Yu, Na,Gu, Linghui,Li, Zheyu,Ma, Wenbo,&Zhao, Fei.(2023).Redox-neutral rhodium(iii)-catalyzed divergent synthesis of tetrasubstituted 1,3-enynes and alkynylated benzofurans.ORGANIC & BIOMOLECULAR CHEMISTRY,21(1),147-152. |
| MLA | Gong, Xin,et al."Redox-neutral rhodium(iii)-catalyzed divergent synthesis of tetrasubstituted 1,3-enynes and alkynylated benzofurans".ORGANIC & BIOMOLECULAR CHEMISTRY 21.1(2023):147-152. |
入库方式： OAI收割
来源：上海药物研究所
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