Research progress on effects of traditional Chinese medicine on myocardial ischemia-reperfusion injury: A review
文献类型：期刊论文
| 作者 | Xing, Na1,2; Long, Xiao-Tong1,3; Zhang, Hui-Juan1,4; Fu, Li-Dan1,4; Huang, Jian-Yuan1,5; Chaurembo, Abdallah Iddy1,2,6; Chanda, Francis1,2,6; Xu, Yun-Jing1,2,6; Shu, Chi1,7; Lin, Kai-Xuan8,9 |
| 刊名 | FRONTIERS IN PHARMACOLOGY
 |
| 出版日期 | 2022-12-06 |
| 卷号 | 13页码:23 |
| 关键词 | myocardial ischemia-reperfusion injury pathogenesis traditional Chinese medicine cardioprotective effects molecular mechanisms |
| DOI | 10.3389/fphar.2022.1055248 |
| 通讯作者 | Yang, Ke(yangyongyao168@sina.com) ; Lin, Han-Bin(linhanbin@simm.ac.cn) |
| 英文摘要 | Ischemic heart disease (IHD) is a high-risk disease in the middle-aged and elderly population. The ischemic heart may be further damaged after reperfusion therapy with percutaneous coronary intervention (PCI) and other methods, namely, myocardial ischemia-reperfusion injury (MIRI), which further affects revascularization and hinders patient rehabilitation. Therefore, the investigation of new therapies against MIRI has drawn great global attention. Within the long history of the prevention and treatment of MIRI, traditional Chinese medicine (TCM) has increasingly been recognized by the scientific community for its multi-component and multi-target effects. These multi-target effects provide a conspicuous advantage to the anti-MIRI of TCM to overcome the shortcomings of single-component drugs, thereby pointing toward a novel avenue for the treatment of MIRI. However, very few reviews have summarized the currently available anti-MIRI of TCM. Therefore, a systematic data mining of TCM for protecting against MIRI will certainly accelerate the processes of drug discovery and help to identify safe candidates with synergistic formulations. The present review aims to describe TCM-based research in MIRI treatment through electronic retrieval of articles, patents, and ethnopharmacology documents. This review reported the progress of research on the active ingredients, efficacy, and underlying mechanism of anti-MIRI in TCM and TCM formulas, provided scientific support to the clinical use of TCM in the treatment of MIRI, and revealed the corresponding clinical significance and development prospects of TCM in treating MIRI. |
| WOS关键词 | ENDOPLASMIC-RETICULUM STRESS ; HYPOXIA-REOXYGENATION INJURY ; ISCHEMIA/REPERFUSION INJURY ; INDUCED APOPTOSIS ; SALVIANOLIC ACID ; ASTRAGALUS POLYSACCHARIDE ; DIABETIC CARDIOMYOPATHY ; OXIDATIVE STRESS ; RAT HEARTS ; PROTECTS |
| 资助项目 | National Natural Science Foundation of China ; High-level New R&D Institute of Department of Science and Technology of Guangdong Province ; High-level Innovative Research Institute of Department of Science and Technology of Guangdong Province ; [82100391] ; [2019B090904008] ; [2021B0909050003] |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| 出版者 | FRONTIERS MEDIA SA |
| WOS记录号 | WOS:000899450000001 |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/304252]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Yang, Ke; Lin, Han-Bin |
| 作者单位 | 1.SIMM CAS, Zhongshan Inst Drug Discovery, Zhongshan, Guangdong, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai, Peoples R China 3.Univ Toronto, Dept Physiol, Toronto, ON, Canada 4.Zunyi Med Univ, Coll Pharm, Zunyi, Guizhou, Peoples R China 5.Southern Med Univ, Coll Pharm, Guangzhou, Guangdong, Peoples R China 6.Univ Chinese Acad Sci, Beijing, Peoples R China 7.Shenyang Agr Univ, Coll Food Sci, Shenyang, Liaoning, Peoples R China 8.Guangzhou Univ Chinese Med, Zhongshan Hosp Tradit Chinese Med, Dept Cardiol, Zhongshan Hosp, Zhongshan, Guangdong, Peoples R China 9.Guangzhou Univ Chinese Med, Guangzhou, Peoples R China 10.China Jiliang Univ, Coll Life Sci, Hangzhou, Zhejiang, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xing, Na,Long, Xiao-Tong,Zhang, Hui-Juan,et al. Research progress on effects of traditional Chinese medicine on myocardial ischemia-reperfusion injury: A review[J]. FRONTIERS IN PHARMACOLOGY,2022,13:23. |
| APA | Xing, Na.,Long, Xiao-Tong.,Zhang, Hui-Juan.,Fu, Li-Dan.,Huang, Jian-Yuan.,...&Lin, Han-Bin.(2022).Research progress on effects of traditional Chinese medicine on myocardial ischemia-reperfusion injury: A review.FRONTIERS IN PHARMACOLOGY,13,23. |
| MLA | Xing, Na,et al."Research progress on effects of traditional Chinese medicine on myocardial ischemia-reperfusion injury: A review".FRONTIERS IN PHARMACOLOGY 13(2022):23. |
入库方式： OAI收割
来源：上海药物研究所
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