Design strategies and applications of smart optical probes in the second near-infrared window
文献类型：期刊论文
| 作者 | Chang, Baisong1; Chen, Jie1; Bao, Jiasheng1; Dong, Kangfeng1; Chen, Si2; Cheng, Zhen3,4 |
| 刊名 | ADVANCED DRUG DELIVERY REVIEWS
 |
| 出版日期 | 2023 |
| 卷号 | 192页码:35 |
| 关键词 | Second near-infrared spectral window Molecular engineering Stimuli-responsive imaging Bioimaging Theranostics |
| ISSN号 | 0169-409X |
| DOI | 10.1016/j.addr.2022.114637 |
| 通讯作者 | Chen, Si(vanessa@csu.edu.cn) ; Cheng, Zhen(zcheng@simm.ac.cn) |
| 英文摘要 | Over the last decade, a series of synergistic advances in the synthesis chemistries and imaging instru-ments have largely boosted a significant revolution, in which large-scale biomedical applications are now benefiting from optical bioimaging in the second near-infrared window (NIR-II, 1000-1700 nm). The large tissue penetration and limited autofluorescence associated with long-wavelength imaging improve translational potential of NIR-II imaging over common visible-light (400-650 nm) and NIR-I (750-900 nm) imaging, with ongoing profound effects on the studies of precision medicine. Unfortunately, the majority of NIR-II probes are designed as "always-on" luminescent imaging contrasts, continuously generating unspecific signals regardless of whether they reach pathological locations. Thus, in vivo imaging by traditional NIR-II probes usually suffers from weak detect precision due to high back-ground noise. In this context, the advances of optical imaging now enter into an era of precise control of NIR-II photophysical kinetics. Developing NIR-II optical probes that can efficiently activate their lumines-cent signal in response to biological targets of interest and substantially suppress the background inter-ferences have become a highly prospective research frontier. In this review, the merits and demerits of optical imaging probes from visible-light, NIR-I to NIR-II windows are carefully discussed along with the lens of stimuli-responsive photophysical kinetics. We then highlight the latest development in engi-neering methods for designing smart NIR-II optical probes. Finally, to appreciate such advances, chal-lenges and prospect in rapidly growing study of smart NIR-II probes are addressed in this review.(c) 2022 Elsevier B.V. All rights reserved. |
| WOS关键词 | AG2S QUANTUM DOTS ; HYDROGEN-SULFIDE ; GLUTATHIONE METABOLISM ; TUMOR MICROENVIRONMENT ; FLUORESCENT-PROBES ; OXIDATIVE STRESS ; II FLUORESCENCE ; RATIONAL DESIGN ; CONTRAST ; CANCER |
| 资助项目 | National Natural Science Foundation of China, China[U2267221] ; Shanghai Municipal Science and Technology Major Project, China ; Natural Science Foundation of Hubei Province, China[2021CFB344] ; Young Top-notch Talent Cultivation Program of Hubei Province, China |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000894968400006 |
| 出版者 | ELSEVIER |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/304312]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Chen, Si; Cheng, Zhen |
| 作者单位 | 1.Wuhan Univ Technol, State Key Lab Adv Technol Mat Synth & Proc, Wuhan 430070, Peoples R China 2.Cent South Univ, Xiangya Hosp, Dept Neurol, Xiangya Rd 88, Changsha 410008, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Mol Imaging Ctr, State Key Lab Drug Res, Shanghai 201203, Peoples R China 4.Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, Yantai 264000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Chang, Baisong,Chen, Jie,Bao, Jiasheng,et al. Design strategies and applications of smart optical probes in the second near-infrared window[J]. ADVANCED DRUG DELIVERY REVIEWS,2023,192:35. |
| APA | Chang, Baisong,Chen, Jie,Bao, Jiasheng,Dong, Kangfeng,Chen, Si,&Cheng, Zhen.(2023).Design strategies and applications of smart optical probes in the second near-infrared window.ADVANCED DRUG DELIVERY REVIEWS,192,35. |
| MLA | Chang, Baisong,et al."Design strategies and applications of smart optical probes in the second near-infrared window".ADVANCED DRUG DELIVERY REVIEWS 192(2023):35. |
入库方式： OAI收割
来源：上海药物研究所
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