Antitumor pharmacological research in the era of personalized medicine
文献类型：期刊论文
| 作者 | Huang, Min1,2 ; Geng, Mei-yu1,2; Ding, Jian1,2
|
| 刊名 | ACTA PHARMACOLOGICA SINICA
 |
| 出版日期 | 2022-12-01 |
| 卷号 | 43期号:12页码:3015-3020 |
| 关键词 | personalized medicine anticancer drug discovery oncogene addiction non-oncogene addiction combination therapy |
| ISSN号 | 1671-4083 |
| DOI | 10.1038/s41401-022-01023-0 |
| 通讯作者 | Ding, Jian(jding@simm.ac.cn) |
| 英文摘要 | Anticancer drug discovery has yielded unprecedented progress in recent decades, resulting in the approval of innovative treatment options for patients and the successful implementation of personalized medicine in clinical practice. This remarkable progress has also reshaped the research scope of pharmacological research. This article, as a tribute to cancer research at Shanghai Institute of Materia Medica in celebration of the institute's 90th birthday, provides an overview of the conceptual revolution occurring in anticancer therapy, and summarizes our recent progress in the development of molecularly targeted therapeutics and exploration of new strategies in personalized medicine. With this review, we hope to provide a glimpse into how antitumor pharmacological researchers have embraced the new era of personalized medicine research and to propose a future path for anticancer drug discovery and pharmacological research. |
| WOS关键词 | THERAPEUTIC RESPONSE ; ANTICANCER THERAPY ; CANCER-THERAPY ; INHIBITORS ; FGFR ; BIOMARKERS ; ADDICTION ; ONCOGENE |
| 资助项目 | National Natural Science Foundation of China for Innovation Research Group[81821005] |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000887859600001 |
| 出版者 | NATURE PUBL GROUP |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/304395]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Ding, Jian |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Huang, Min,Geng, Mei-yu,Ding, Jian. Antitumor pharmacological research in the era of personalized medicine[J]. ACTA PHARMACOLOGICA SINICA,2022,43(12):3015-3020. |
| APA | Huang, Min,Geng, Mei-yu,&Ding, Jian.(2022).Antitumor pharmacological research in the era of personalized medicine.ACTA PHARMACOLOGICA SINICA,43(12),3015-3020. |
| MLA | Huang, Min,et al."Antitumor pharmacological research in the era of personalized medicine".ACTA PHARMACOLOGICA SINICA 43.12(2022):3015-3020. |
入库方式： OAI收割
来源：上海药物研究所
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