The microbiota-gut-brain axis hypothesis has attracted more and more attention in the research of the pathogenesis of schizophrenia. Previous research has preliminarily investigated the relationship between the composition of gut microbiota and the brain imaging and clinical manifestation of patients with schizophrenia, but the specific action path is still unclear. This research summarized the latest research progress, and on this basis, proposed the mechanism hypothesis of gut microbiota affecting the brain structure and function of patients with schizophrenia. The related contents will provide a theoretical basis for further elucidation of the pathological mechanism of schizophrenia and for incorporating gut microbiota into the assessment and intervention of schizophrenia.

目的 探讨情绪调节策略的代际传递以及家庭阅读和母子亲密在其中的中介作用,为提高儿童的情绪调节能力提供参考。方法 2021年12月采用父母情绪调节策略问卷、家庭阅读问卷、亲子关系量表以及学龄前儿童情绪调节策略量表对398名3～6岁儿童的母亲进行测量,采用SPSS26.0进行相关分析和运用AMOS26.0建立结构方程模型,考察母亲认知重评情绪调节策略对儿童的积极情绪调节策略的影响以及家庭阅读和母子亲密在其中的多重中介作用。结果 1)本科及以上学历母亲的儿童问题解决能力显著高于中专及以下学历母亲的儿童(F=5.37,P<0.01)。2)母亲的认知重评情绪调节策略与儿童的积极情绪调节策略、家庭阅读和母子亲密呈显著正相关(r=0.150～0.348,P<0.05);家庭阅读与儿童的积极情绪调节策略和母子亲密呈显著正相关(r=0.151～0.279,P<0.01);母子亲密与儿童的认知重建和替代活动积极调节策略呈显著正相关(r=0.200～0.219,P<0.01)。3)母亲的认知重评情绪调节策略显著预测儿童的积极情绪调节策略(β=0.32,t=5.73,P<0.001),家庭阅读和母子亲密在情绪调节策略的代际传递中起中介作用,中介效应分别为4.37%、12.34%;同时这两者形成的链式中介效应为1.03%。结论 母亲的情绪调节策略是影响学龄前儿童情绪调节策略的重要影响因素,家庭阅读和母子亲密在其中起链式中介作用。