Label-free and selective cholesterol detection based on multilayer functional structure coated fiber fabry-perot interferometer probe
文献类型:期刊论文
作者 | Wang, Ruiduo4,5; Yan, Minglu4; Jiang, Man4; Li, Yang3; Kang, Xin1,2; Hu, Mingxuan4; Liu, Beibei4; He, Zhengquan5; Kong, Depeng5 |
刊名 | ANALYTICA CHIMICA ACTA |
出版日期 | 2023-04-29 |
卷号 | 1252 |
ISSN号 | 0003-2670;1873-4324 |
关键词 | Cholesterol Fabry-Perot cavity Biosensor Beta-cyclodextrin Graphene oxide |
DOI | 10.1016/j.aca.2023.341051 |
产权排序 | 1 |
英文摘要 | A reflective fiber-optic Fabry-Perot cavity probe sensor is proposed to selectively measure cholesterol concentration by insert single mode fiber into ceramic tube and immobilize epoxy resin (ER)/graphene oxide (GO)/ beta-cyclodextrin (beta-CD) multi-layer film onto end face of ceramic tube. EDC/NHS activated GO is selected to form chemical binding with beta-CD, and beta-CD is the sensitive materials to bind with cholesterol molecules. With multi-layer film assisted, the sensitivity of sensor to cholesterol concentration can reach 3.92 nm/mM and the limit of detection reaches 3.48 mu M. In addition, 4 mM hemoglobin, glucose and ascorbic acid are doped into a set cholesterol sample and verified the highly selectivity of sensing cholesterol. Furthermore, the reproducibility was proved by measure the spectrum of four sensors with same fabrication process, and the reusability was also proved by repeated measurements. Overall, the sensor features with high mechanical strength, ease of fabrication, real-time monitoring, low cost and ease for measurement that given by probe structure. Therefore, the sensor provides a remarkable analytical platform for biosensing applications. |
语种 | 英语 |
出版者 | ELSEVIER |
WOS记录号 | WOS:000962757500001 |
源URL | [http://ir.opt.ac.cn/handle/181661/96422] |
专题 | 西安光学精密机械研究所_先进光电与生物材料研发中心 |
通讯作者 | Jiang, Man; Kong, Depeng |
作者单位 | 1.Northwestern Polytech Univ, Sch Phys Sci & Technol, Shaanxi Key Lab Opt Informat Technol, Xian 710129, Peoples R China 2.Northwestern Polytech Univ, Sch Phys Sci & Technol, Key Lab Light Field Manipulat & Informat Acquisit, Minist Ind & Informat Technol, Xian 710129, Peoples R China 3.38th Res Inst China Elect Technol Grp Corp, Key Lab Aperture Array & Space Applicat, Hefei 230000, Peoples R China 4.Northwest Univ, Inst Photon & Photon Technol, Int Collaborat Ctr Photoelect Technol & Nano Funct, Sch Phys, Xian 710069, Peoples R China 5.Chinese Acad Sci, Xian Inst Opt & Precis Mech, State Key Lab Transient Opt & Photon, Xian 710119, Peoples R China |
推荐引用方式 GB/T 7714 | Wang, Ruiduo,Yan, Minglu,Jiang, Man,et al. Label-free and selective cholesterol detection based on multilayer functional structure coated fiber fabry-perot interferometer probe[J]. ANALYTICA CHIMICA ACTA,2023,1252. |
APA | Wang, Ruiduo.,Yan, Minglu.,Jiang, Man.,Li, Yang.,Kang, Xin.,...&Kong, Depeng.(2023).Label-free and selective cholesterol detection based on multilayer functional structure coated fiber fabry-perot interferometer probe.ANALYTICA CHIMICA ACTA,1252. |
MLA | Wang, Ruiduo,et al."Label-free and selective cholesterol detection based on multilayer functional structure coated fiber fabry-perot interferometer probe".ANALYTICA CHIMICA ACTA 1252(2023). |
入库方式: OAI收割
来源:西安光学精密机械研究所
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