MHC II DRB variation and trans-species polymorphism in the golden snub-nosed monkey (Rhinopithecus roxellana)
文献类型：期刊论文
| 作者 | Luo MaoFang2,3; Pan HuiJuan |
| 刊名 | CHINESE SCIENCE BULLETIN
 |
| 出版日期 | 2013 |
| 卷号 | 58期号:18页码:2119-2127 |
| 关键词 | golden snub-nosed monkey major histocompatibility complex microsatellite mitochondrial D-loop |
| ISSN号 | 1001-6538 |
| DOI | 10.1007/s11434-013-5713-6 |
| 文献子类 | Article |
| 英文摘要 | Genetic variation is generally believed to be important in studying endangered species' adaptive potential. Early studies assessed genetic diversity using nearly neutral markers, such as microsatellite loci and mitochondrial DNA (mtDNA), which are very informative for phylogenetic and phylogeographic reconstructions. However, the variation at these loci cannot provide direct information on selective processes involving the interaction of individuals with their environment, or on the capability to resist continuously evolving pathogens and parasites. The importance of genetic diversity at informative adaptive markers, such as major histocompatibility complex (MHC) genes, is increasingly being realized, especially in endangered, isolated species. Small population size and isolation make the golden snub-nosed monkey (Rhinopithecus roxellana) particularly susceptible to genetic variation losses through inbreeding and restricted gene flow. In this study, we compared the genetic variation and population structure of microsatellites, mtDNA, and the most relevant adaptive region of the MHC II-DRB genes in the golden snub-nosed monkey. We examined three Chinese R. roxellana populations and found the same variation patterns in all gene regions, with the population from Shennongjia population, Hubei Province, showing the lowest polymorphism among three populations. Genetic drift that outweighed balancing selection and the founder effect in these populations may explain the similar genetic variation pattern found in these neutral and adaptive genes. |
| 学科主题 | Multidisciplinary Sciences |
| 出版地 | BEIJING |
| 电子版国际标准刊号 | 1861-9541 |
| WOS关键词 | HISTOCOMPATIBILITY COMPLEX VARIATION ; LONG-TERM SURVIVAL ; GENETIC DIVERSITY ; LINKAGE DISEQUILIBRIUM ; PHYLOGENETIC ANALYSIS ; SELECTION ; RECOMBINATION ; POPULATIONS ; EVOLUTION ; ALLELES |
| WOS研究方向 | Science Citation Index Expanded (SCI-EXPANDED) |
| 语种 | 英语 |
| WOS记录号 | WOS:000321629800005 |
| 出版者 | SCIENCE PRESS |
| 资助机构 | National Natural Science Foundation of China(National Natural Science Foundation of China (NSFC)) ; Project of Public Benefit ; Beijing Forestry University Young Scientist Fund ; State Forestry Administration of China |
| 源URL | [http://ir.ibcas.ac.cn/handle/2S10CLM1/28098]  |
| 专题 | 植被与环境变化国家重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst Bot, Key Lab Vegetat & Environm Change, Beijing 100093, Peoples R China 2.Chinese Acad Sci, Inst Zool, Key Lab Anim Ecol & Conservat Biol, Beijing 100101, Peoples R China 3.Beijing Forestry Univ, Coll Nat Conservat, Beijing 100083, Peoples R China |
| 推荐引用方式 GB/T 7714 | Luo MaoFang,Pan HuiJuan. MHC II DRB variation and trans-species polymorphism in the golden snub-nosed monkey (Rhinopithecus roxellana)[J]. CHINESE SCIENCE BULLETIN,2013,58(18):2119-2127. |
| APA | Luo MaoFang,&Pan HuiJuan.(2013).MHC II DRB variation and trans-species polymorphism in the golden snub-nosed monkey (Rhinopithecus roxellana).CHINESE SCIENCE BULLETIN,58(18),2119-2127. |
| MLA | Luo MaoFang,et al."MHC II DRB variation and trans-species polymorphism in the golden snub-nosed monkey (Rhinopithecus roxellana)".CHINESE SCIENCE BULLETIN 58.18(2013):2119-2127. |
入库方式： OAI收割
来源：植物研究所
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