Proteomic evaluation of genetically modified crops: current status and challenges
文献类型：期刊论文
| 作者 | Gong, Chun Yan; Wang, Tai
|
| 刊名 | FRONTIERS IN PLANT SCIENCE
 |
| 出版日期 | 2013 |
| 卷号 | 4 |
| 关键词 | genetically modified crops biological safety unintended effects substantial equivalence proteome and proteomics |
| ISSN号 | 1664-462X |
| DOI | 10.3389/fpls.2013.00041 |
| 文献子类 | Review |
| 英文摘要 | Hectares of genetically modified (GM) crops have increased exponentially since 1996, when such crops began to be commercialized. GM biotechnology, together with conventional breeding, has become the main approach to improving agronomic traits of crops. However, people are concerned about the safety of GM crops, especially GM-derived food and feed. Many efforts have been made to evaluate the unintended effects caused by the introduction of exogenous genes. Omics techniques have advantages over targeted analysis in evaluating such crops because of their use of high-throughput screening. Proteins are key players in gene function and are directly involved in metabolism and cellular development or have roles as toxins, antinutrients, or allergens, which are essential for human health. Thus, proteomics can be expected to become one of the most useful tools in safety assessment. This review assesses the potential of proteomics in evaluating various GM crops. We further describe the challenges in ensuring homogeneity and sensitivity in detection techniques. |
| 学科主题 | Plant Sciences |
| 出版地 | LAUSANNE |
| WOS关键词 | 2-DIMENSIONAL GEL-ELECTROPHORESIS ; SUBSTANTIAL EQUIVALENCE ; PROTEASE INHIBITOR ; MAIZE VARIETIES ; EXPRESSION ; SAFETY ; RICE ; WHEAT ; GENE ; SEEDS |
| WOS研究方向 | Science Citation Index Expanded (SCI-EXPANDED) |
| 语种 | 英语 |
| WOS记录号 | WOS:000329582800001 |
| 出版者 | FRONTIERS MEDIA SA |
| 资助机构 | Chinese Ministry of Agriculture(Ministry of Agriculture & Rural Affairs) |
| 源URL | [http://ir.ibcas.ac.cn/handle/2S10CLM1/27791]  |
| 专题 | 中科院植物分子生理学重点实验室 |
| 作者单位 | Chinese Acad Sci, Key Lab Plant Mol Physiol, Inst Bot, Beijing 100093, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gong, Chun Yan,Wang, Tai. Proteomic evaluation of genetically modified crops: current status and challenges[J]. FRONTIERS IN PLANT SCIENCE,2013,4. |
| APA | Gong, Chun Yan,&Wang, Tai.(2013).Proteomic evaluation of genetically modified crops: current status and challenges.FRONTIERS IN PLANT SCIENCE,4. |
| MLA | Gong, Chun Yan,et al."Proteomic evaluation of genetically modified crops: current status and challenges".FRONTIERS IN PLANT SCIENCE 4(2013). |
入库方式： OAI收割
来源：植物研究所
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