中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Molecular imprinted electrochemical sensor for ovalbumin detection based on boronate affinity and signal amplification approach

文献类型:期刊论文

作者Fu, Hao3; Bai, Zhenyu3; Li, Ping3; Feng, Xiaoyang3; Hu, Xueping3; Song, Xingliang3; Chen, Lingxin1,2
刊名FOOD CHEMISTRY
出版日期2023-05-30
卷号409页码:8
ISSN号0308-8146
关键词Molecular imprinted electrochemical sensor Boronate affinity Glycoprotein Signal amplification
DOI10.1016/j.foodchem.2022.135292
通讯作者Hu, Xueping(xuephu@yeah.net) ; Song, Xingliang(xlssong@yeah.net)
英文摘要Ovalbumin (OVA), a class of glycoproteins, is the main allergen in hen egg white that often causes allergies in humans, especially in babies. Therefore, it is pivotal to be able to detect and separate OVA. This work presents an ingenious sandwich-structured magnetic molecular imprinted electrochemical sensor for OVA detection by uti-lizing boronate affinity and signal amplification strategy. With anti-OVA antibody-modified gold nanoparticles (AuNPs) as amplifiers, the imprinted cavities in the probe could capture protein to form a sandwich structure. Due to its specific recognition of antibody and molecular imprinted polymers and the signal amplification of AuNPs, the sensor had good selectivity and sensitivity toward OVA and a low detection limit of 3.0 fg/mL. The sensor also had excellent stability and could satisfactorily detect OVA in real red wine samples.
WOS关键词S-OVALBUMIN ; GLYCOSYLATION ; NANOPARTICLES
WOS研究方向Chemistry ; Food Science & Technology ; Nutrition & Dietetics
语种英语
WOS记录号WOS:000915044100001
资助机构National Natural Science Foundation of China ; Natural Science Foundation of Shandong Province ; Key Research and Development Program of Linyi City
源URL[http://ir.yic.ac.cn/handle/133337/32573]  
专题烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
烟台海岸带研究所_山东省海岸带环境工程技术研究中心
通讯作者Hu, Xueping; Song, Xingliang
作者单位1.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
3.Linyi Univ, Sch Chem & Chem Engn, Linyi 276005, Peoples R China
推荐引用方式
GB/T 7714
Fu, Hao,Bai, Zhenyu,Li, Ping,et al. Molecular imprinted electrochemical sensor for ovalbumin detection based on boronate affinity and signal amplification approach[J]. FOOD CHEMISTRY,2023,409:8.
APA Fu, Hao.,Bai, Zhenyu.,Li, Ping.,Feng, Xiaoyang.,Hu, Xueping.,...&Chen, Lingxin.(2023).Molecular imprinted electrochemical sensor for ovalbumin detection based on boronate affinity and signal amplification approach.FOOD CHEMISTRY,409,8.
MLA Fu, Hao,et al."Molecular imprinted electrochemical sensor for ovalbumin detection based on boronate affinity and signal amplification approach".FOOD CHEMISTRY 409(2023):8.

入库方式: OAI收割

来源:烟台海岸带研究所

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