主观认知下降老年人的舞蹈干预效果一一来自多模态脑成像的证据
文献类型：学位论文
| 作者 | 孙雅雯
|
| 答辩日期 | 2023-06 |
| 文献子类 | 硕士 |
| 授予单位 | 中国科学院大学 |
| 授予地点 | 中国科学院心理研究所 |
| 其他责任者 | 陈天勇 |
| 关键词 | 主观认知下降 舞蹈 生活方式 认知功能 磁共振成像 |
| 学位名称 | 理学硕士 |
| 学位专业 | 应用心理 |
| 其他题名 | Dance intervention impact on older adults with Subjective Cognitive Decline:Evidence from a Multi-Model MRI Study |
| 中文摘要 | Objective: The aging degree of Chinese population is increasing, and the high incidence of cognitive impairment causes burden for individuals, families and society. Subjective cognitive decline (SCD) is known as the pre-clinical stage of Alzheimer's disease (AD), which echoes the active health concept, as one of the hot research points in AD prevention. However, due to the relatively new concept of SCD, there are fewer non-drug interventions for it, among which, there are fewer studies on lifestyle intervention, and the relevant evidence is insufficient. Dance is a multi-component lifestyle that integrates physical movement, cognitive activity, social interaction and other component. Studies have shown that dance can promote physical, cognitive, emotional and other functions in older adults, but whether dance can affect cognitive function and brain plasticity in older adults is still in its infancy. Meanwhile, no studies have explored the effect of dance on older adults with SCD. Therefore, the aim of this study was to examine the effects of dance training on cognitive function and brain structure and function in older adults with SCD. Methods: A total of 55 older adults with SCD (mean age 65.1) were included in this study using a single-blind randomised controlled trial (RCT) and randomised to the intervention group (n=27) and control group (n=28). The intervention group received 1.5 hours of dance training twice a week for 21 weeks. The dance courses included healthy walking dance, aerobics, duet dance, group dance, etc. The dance difficulty was progressive. The control group was designed to have four health talks once a month on issues commonly faced by older adults. Pre一and post-test measurement domains included cognitive function and Multi-Model MRI (structural MRI, and resting-state fMRI scans). Results: After 21 weeks of dance training, the results revealed that: (1) Dance training could improve cognitive functions of older adults with SCD. Compared with the control, the scores of episodic memory, verbal comprehension, and visuospatial ability of older adults with SCD in the intervention group improved, but working memory and processing speed did not improve significantly after the training. (2) Dance training can change the gray matter volume of the brain, and training can increase the gray matter volume of the cerebellum, and delay the shrinkage of gray matter volume in the cerebellum, insula, putamen, and superior temporal gyros regions. (3) Dance training can change the resting state functional connectivity of the brain. The dance intervention delayed the rsFC decrease of the intervention group in the cerebellum with default network regions such as precuneus and sensory-motor network regions such as precentral gyros; increased rsFC of the intervention group in the insula with supplementary motor areas, cerebellum with default network regions such as parahippocampus, DAN network with frontoparietal network regions such as frontal middle gyros; and decreased rsFC of the intervention group in the DMN network with the thalamus and DAN network with the frontoparietal network regions such as the dorsolateral superior frontal gyros. Also, these changes in rsFC were associated with changes in some tests of cognitive function. Conclusion: Dance training can promote cognitive function and brain structure and function in older adults with SCD. Overall, dance is an effective, economical and promising intervention for cognitive decline. |
| 英文摘要 | 目的:我国人口老龄化程度日趋加重，认知障碍高发，为个人、家庭、社会造成负担。主观认知下降(Subjective Cognitive Decline, SCD)被认为是阿尔茨海默病(Alzheimer's disease, AD)的临床前阶段，与我国提出的主动健康理念与模式交相呼应，是当前AD预防的研究热点之一。然而，由于SCD概念较新，对其的非药物干预较少，其中，生活方式干预研究更少，相关证据不足。 舞蹈是一种集身体运动、认知活动、社交等多种刺激于一体的多成分生活方式。已有研究表明，舞蹈能促进老年人身体、认知、情绪等多种功能，但关于舞蹈能否影响老年人认知功能及脑结构与功能，目前研究尚处于起步阶段。同时，未有研究探索过舞蹈对SCD老年人的影响。因此，本研究旨在考察舞蹈训练对于SCD老年人认知功能以及脑结构与功能的影响。 方法:本研究采用单盲随机对照试验(RCT，共纳入55名SCD老年人(平均年龄65.1岁)，随机进入舞蹈干预组(27人)和健康讲座对照组(28人)。干预组进行舞蹈训练，为期21周、每周两次、每次1.5小时，舞蹈课程内容包括健康走步舞、有氧健身操、双人舞、多人集体舞等形式，舞蹈难度循序渐进。对照组进行健康讲座，一月一次、共四次，内容为老年人普遍面临的身心健康问题，包括J漫病防治、睡眠问题等。前后测量认知功能与多模态脑成像(结构像MRI、静息态fMRI扫描)。 结果:21周舞蹈干预后，结果表明: （1)舞蹈干预改善SCD老年人认知功能。与对照组相比，干预组SCD老年人情景记忆、言语理解、视觉空间能力成绩提高，但工作记忆、加工速度在训练后未明显改善; (2)舞蹈干预改变脑灰质体积。与对照组相比，干预增加干预组SCD老年人小脑灰质体积，延缓其小脑、脑岛、壳核、颗上回区域灰质体积萎缩; (3)舞蹈干预改变脑静息态功能连接。与对照组相比，干预延缓了干预组小脑与楔前叶等默认网络区域、中央前回等感觉运动网络区域的rsFC降低;增加了干预组脑岛与辅助运动区、小脑与旁海马等默认网络区域，DAN网络与额中回等额顶网络区域的rsFC;降低了干预组DMN网络与丘脑，DAN网络与背外侧额上回等额顶网络区域的rsFC。同时，这些rsFC变化与部分认知功能测试变化相关。 结论:舞蹈干预促进SCD老年人认知功能与脑结构与功能。总体来说，舞蹈对于认知衰退是有效、经济、具有发展前景的干预方法。 |
| 语种 | 中文 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/45201]  |
| 专题 | 心理研究所_健康与遗传心理学研究室 |
| 推荐引用方式 GB/T 7714 | 孙雅雯. 主观认知下降老年人的舞蹈干预效果一一来自多模态脑成像的证据[D]. 中国科学院心理研究所. 中国科学院大学. 2023. |
入库方式： OAI收割
来源：心理研究所
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