A general and facile one-pot process of isothiocyanates from amines under aqueous conditions
文献类型：期刊论文
| 作者 | Sun N(孙楠)1; Li B(黎滨)1; Shao JP(邵建平)1; Mo WM(莫卫民)1; Hu BX(胡宝祥)1; Shen ZL(沈振陆)1; Hu XQ(胡信全)1,2 |
| 刊名 | Beilstein Journal of Organic Chemistry
 |
| 出版日期 | 2012 |
| 卷号 | 8页码:61-70 |
| 关键词 | aqueous conditions cyanuric acid isothiocyanates one-pot process organic synthesis primary amines |
| ISSN号 | 1860-5397 |
| 通讯作者 | 莫卫民 ; 胡信全 |
| 英文摘要 | A general and facile one-pot protocol for the preparation of a broad range of alkyl and aryl isothiocyanates has been developed from their corresponding primary amines under aqueous conditions. This synthetic process involves an in situ generation of a dithiocarbamate salt from the amine substrate by reacting with CS2 followed by elimination to form the isothiocyanate product with cyanuric acid as the desulfurylation reagent. The choice of solvent is of decisive importance for the successful formation of the dithiocarbamate salt particularly for highly electron-deficient substrates. This novel and economical method is suitable for scale-up activities. |
| 学科主题 | 物理化学与绿色催化 |
| 收录类别 | SCI |
| 资助信息 | the National Natural Science Foundation of China (NSFC, 20772111;20876149);the project of Science and Technology Department of Zhejiang Province (2009C21013);the Natural Science Foundation of Zhejiang Province (Y407193) |
| 语种 | 英语 |
| WOS记录号 | WOS:000298963900001 |
| 公开日期 | 2013-10-11 |
| 源URL | [http://210.77.64.217/handle/362003/3885]  |
| 专题 | 兰州化学物理研究所_OSSO国家重点实验室 |
| 作者单位 | 1.College of Chemical Engineering and Materials Science, Zhejiang University of Technology, Hangzhou 310014, China 2.State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, China |
| 推荐引用方式 GB/T 7714 | Sun N,Li B,Shao JP,et al. A general and facile one-pot process of isothiocyanates from amines under aqueous conditions[J]. Beilstein Journal of Organic Chemistry,2012,8:61-70. |
| APA | Sun N.,Li B.,Shao JP.,Mo WM.,Hu BX.,...&Hu XQ.(2012).A general and facile one-pot process of isothiocyanates from amines under aqueous conditions.Beilstein Journal of Organic Chemistry,8,61-70. |
| MLA | Sun N,et al."A general and facile one-pot process of isothiocyanates from amines under aqueous conditions".Beilstein Journal of Organic Chemistry 8(2012):61-70. |
入库方式： OAI收割
来源：兰州化学物理研究所
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