3D Bio-Printing Fabrication and Properties of Graphene Dispersion-based Hybrid Scaffolds
文献类型：会议论文
| 作者 | Peng, Jun1,2; Li, Liying1,2; Nie, Yi2,3; Liu, Tianqing1; Song, Kedong1 |
| 出版日期 | 2020-09-16 |
| 会议日期 | July 17, 2020 - July 18, 2020 |
| 会议地点 | Jinan, Shandong, China |
| 关键词 | Tissue - Cell proliferation - Sodium alginate - 3D printers - Contact angle - Degradation - Water absorption - Biocompatibility - Scaffolds (biology) |
| 卷号 | 1622 |
| 期号 | 1 |
| DOI | 10.1088/1742-6596/1622/1/012062 |
| 英文摘要 | Peripheral nerve is an important tissue of human body, which is distributed in various parts of human body, and has the function of connecting central nervous system and other organs. The self-repair ability of the nervous system is poor. However, 3D bio-printed neural tissue-engineered scaffolds offer a promising solution. In this study, graphene (Gr) was dispersed by a certain method, and then blended with gelatin (Gel) and sodium alginate (SA) to prepare a mixed bio-ink. Performance of different ratios of bio-ink was evaluated to determine the best printing ratio of the material. Four groups of Gr/Gel/SA scaffolds (The concentrations of graphene were 0%, 0.02%, 0.08% and 0.2% (w/v%), respectively) were prepared by using 3D printing technology. The mechanical strength, contact angle, degradation rate and water absorption of bio-scaffolds were compared to select the most suitable scaffold to support cell proliferation and differentiation, PC12 cells were used to study the biocompatibility of the scaffolds. This article aims to get the most optimized scaffolds. 漏 Published under licence by IOP Publishing Ltd. |
| 项目编号 | This work was supported by the National Natural Science Foundation of China (31670978/31370991/21676041), the Fok Ying Tung Education Foundation (132027), the State Key Laboratory of Fine Chemicals (KF1111) and the Natural Science Foundation of Liaoning Province (20180510028) and the Fundamental Research Funds for the Central Universities (DUT20ZD206). |
| 资助机构 | IOP Publishing Ltd |
| 会议录 | 6th Annual International Workshop on Materials Science and Engineering, IWMSE 2020
 |
| 学科主题 | Graphene |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/59274]  |
| 作者单位 | 1.State Key Laboratory of Fine Chemicals, Dalian R and D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian; 116024, China 2.Zhengzhou Institute of Emerging Industrial Technology, Zhengzhou; 450000, China 3.Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing; 100190, China |
| 推荐引用方式 GB/T 7714 | Peng, Jun,Li, Liying,Nie, Yi,et al. 3D Bio-Printing Fabrication and Properties of Graphene Dispersion-based Hybrid Scaffolds[C]. 见:. Jinan, Shandong, China. July 17, 2020 - July 18, 2020. |
入库方式： OAI收割
来源：过程工程研究所
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