The effect of collagen coating on surface biocompatibility of the titanium alloys
文献类型：会议论文
| 作者 | Gao, Jianping1,2; Li, Saina1,2; Zhang, Lun1,2; Zhang, Yang2; Chen, Yi3; Xing, Fangyu2; Kong, Yingjun1,2; Luo, Xi1,2; Zhang, Guifeng1,2 |
| 出版日期 | 2021-08-13 |
| 会议日期 | August 13, 2021 - August 15, 2021 |
| 关键词 | Coatings - Collagen - Biocompatibility |
| DOI | 10.1145/3502060.3502144 |
| 英文摘要 | Titanium alloys coated with collagen have been widely used to improve their biocompatibility. In this study, the titanium alloys were coated with type I collagen (Col I) and type II collagen (Col II), respectively. The coating amount was quantified with HPLC/MS. Their biocompatibility was evaluated and the effects of collagen types on cell differentiation were compared by cellular proteins identification and quantification. The quantity of Col I and Col II coated on titanium alloy were 0.813卤0.015 mg and 0.774卤0.013 mg, respectively. Mouse Col I and fibronectin were abundantly expressed within Col I group. The most abundant proteins in Col II group were osteopontin and prelamin-A/C. In conclusion, the collagen coating could improve the biocompatibility of titanium alloy materials, and different types of collagen could induce cell to express proteins with various functions. 漏 2021 Owner/Author. |
| 项目编号 | Science and Technology Program of Guangzhou, China, No. 201803010086 ; National K R & D Program of China, No. 2018YFA0108200 ; National K R & D Program of China, No. 2018YFC1106402. |
| 会议录 | ACM International Conference Proceeding Series
 ; 2021 International Symposium on Biomedical Engineering and Computational Biology, BECB 2021
|
| 会议录出版者 | Association for Computing Machinery |
| 学科主题 | Titanium Alloys |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/59633]  |
| 作者单位 | 1.School of Chemical and Engineering, University of Chinese, Academy of Sciences, Beijing; 100049, China 2.National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing; 100190, China 3.Beijing Biosis Healing Biological, Technology Co Ltd, Beijing; 100026, China |
| 推荐引用方式 GB/T 7714 | Gao, Jianping,Li, Saina,Zhang, Lun,et al. The effect of collagen coating on surface biocompatibility of the titanium alloys[C]. 见:. August 13, 2021 - August 15, 2021. |
入库方式： OAI收割
来源：过程工程研究所
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