Preparation and Properties of Decellularized Sheep Kidney Derived Matrix Scaffolds
文献类型：会议论文
| 作者 | Zheng, Le2; Zheng, Shuangshuang4; Chen, Zilong2; Li, Xiangqin2; Liu, Chunyan5; Bai, Jie1; Jiang, Daqing1; Nie, Yi4,6; Zhang, Jingying3; Liu, Tianqing2 |
| 出版日期 | 2022-01-10 |
| 会议日期 | November 26, 2021 - November 28, 2021 |
| 关键词 | Scaffolds - Pore structure - Scanning electron microscopy - Cell adhesion - Biomechanics - Biocompatibility - Stem cells |
| 卷号 | 2160 |
| 期号 | 1 |
| DOI | 10.1088/1742-6596/2160/1/012014 |
| 英文摘要 | Scaffolds from tissues or organs have nanoscale microstructures. Derived matrix scaffolds prepared by decellularized method can provide more cell attachment sites, which is conducive to cell adhesion, proliferation, differentiation and other physiological activities on scaffolds. In this study, the sheep kidney decellularized matrix scaffold was prepared by the method of decellularization. Due to the poor mechanical properties of the decellularized matrix, the cross linking method was adopted to enhance its mechanical properties. The decellularization efficiency of sheep renal matrix scaffolds was observed by scanning electron microscopy and histological staining, and the biocompatibility of the scaffolds was investigated by inoculating adipose derived stem cells. It was found that the scaffold had good decellularization effect and good pore structure. 漏 2022 Institute of Physics Publishing. All rights reserved. |
| 项目编号 | This work was supported by the National Natural Science Foundation of China (31670978/21676041), the Fok Ying Tung Education Foundation (132027), the State Key Laboratory of Fine Chemicals (KF1111) and the Fundamental Research Funds for the Central Universities (DUT20ZD206/DUT20YG118/DUT21YG113) and the Special funds for key areas of ordinary universities in Guangdong Province (2020ZDZX2013) and the Basic and Applied Basic Research Major Program of Guangdong Province (2020B1515120001). |
| 会议录 | Journal of Physics: Conference Series
 ; 9th Annual International Conference on Material Science and Environmental Engineering, MSEE 2021
|
| 会议录出版者 | IOP Publishing Ltd |
| 学科主题 | Scaffolds (Biology) |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/59644]  |
| 作者单位 | 1.Department of Breast Surgery, Cancer Hospital of China Medical University, Shenyang; 110042, China 2.State Key Laboratory of Fine Chemicals, Dalian R&D Center for Stem Cell and Tissue Engineering, Dalian University of Technology, Dalian; 116024, China 3.The Second Clinical Medical College, Guangdong Medical University, Guangdong, Dongguan; 523808, China 4.Zhengzhou Institute of Emerging Industrial Technology, Zhengzhou; 450000, China 5.Department of Nephrology, Second Affiliated Hospital of Dalian Medical University, Liaoning, Dalian; 116000, China 6.Key Laboratory of Green Process and Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing; 100190, China |
| 推荐引用方式 GB/T 7714 | Zheng, Le,Zheng, Shuangshuang,Chen, Zilong,et al. Preparation and Properties of Decellularized Sheep Kidney Derived Matrix Scaffolds[C]. 见:. November 26, 2021 - November 28, 2021. |
入库方式： OAI收割
来源：过程工程研究所
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