Research progress of microsphere formulations with narrow size distribution
文献类型：期刊论文
| 作者 | Wei, Yi; Ma, Guanghui |
| 刊名 | Huagong Xuebao/CIESC Journal
 |
| 出版日期 | 2021-12-01 |
| 卷号 | 72期号:12页码:6176-6187 |
| 关键词 | Membrane technology - Emulsification - Controlled drug delivery - Particle size - Targeted drug delivery - Drug products |
| ISSN号 | 4381157 |
| DOI | 10.11949/0438-1157.20211117 |
| 英文摘要 | Microsphere preparation is a new type of drug delivery system, and its particle size uniformity is very important. It not only affects the repeatability of product batches, but also affects the application effect. Therefore, manufacture of microspheres with uniform and controlled size play key role in microsphere formulations. Our team has studied on membrane emulsification technology for more than 20 years and successfully prepared various polymer microspheres with uniform and controlled size, and applied them in formulation application. The uniform microsphere formulations have the advantages of green production, low cost, good batch-to-batch repeatability, beneficial to scale up. Furthermore, the uniform size of microsphere helps to study the structure-drug efficacy relationships. The drug-loaded microspheres prepared by our team have been successfully applied in sustained-release formulations, vaccines delivery and malignant tumor treatment. 漏 2021, Editorial Board of CIESC Journal. All right reserved. |
| 学科主题 | Microspheres |
| 出版者 | Materials China |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/60250]  |
| 作者单位 | State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing; 100190, China |
| 推荐引用方式 GB/T 7714 | Wei, Yi,Ma, Guanghui. Research progress of microsphere formulations with narrow size distribution[J]. Huagong Xuebao/CIESC Journal,2021,72(12):6176-6187. |
| APA | Wei, Yi,&Ma, Guanghui.(2021).Research progress of microsphere formulations with narrow size distribution.Huagong Xuebao/CIESC Journal,72(12),6176-6187. |
| MLA | Wei, Yi,et al."Research progress of microsphere formulations with narrow size distribution".Huagong Xuebao/CIESC Journal 72.12(2021):6176-6187. |
入库方式： OAI收割
来源：过程工程研究所
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