A Synchronous Photometry Data Extraction (SPDE) program, performing indiscriminate monitoring of all stars appearing in the same field of view of an astronomical image, is developed by integrating several Astropy affiliated packages to make full use of time series observed by traditional small/medium aperture ground-based telescopes. The complete full-frame stellar photometry data reductions implemented for the two time series of cataclysmic variables: RX J2102.0+3359 and Paloma J0524+4244 produce 363 and 641 optimal light curves, respectively. A cross-identification with SIMBAD finds 23 known stars, of which 16 are red giant-/horizontal-branch stars, 2 W UMa-type eclipsing variables, 2 program stars, an X-ray source and 2 Asteroid Terrestrial-impact Last Alert System variables. Based on the data products from the SPDE program, a follow-up light curve analysis program identifies 32 potential variable light curves, of which 18 are from the time series of RX J2102.0+3359, and 14 are from that of Paloma J0524+4244. They are preliminarily separated into periodic, transient, and peculiar types. By querying for the 58 VizieR online data catalogs, their physical parameters and multi-band brightness spanning X-ray to radio are compiled for future analysis.