中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Temporal transformer-spatial graph convolutional network: an intelligent classification model for anti N-methyl-D-aspartate receptor encephalitis based on electroencephalogram signal

文献类型:期刊论文

作者Dang, Ruochen3,4,5,6; Yu, Tao1,2; Hu, Bingliang3,6; Wang, Yuqi3,6; Pan, Zhibin5; Luo, Rong1,2; Wang, Quan3,6
刊名FRONTIERS MEDIA SA
出版日期2023-08-28
卷号17
关键词anti NMDA receptor encephalitis viral encephalitis EEG transformer graph network classification
ISSN号1662-453X
DOI10.3389/fnins.2023.1223077
产权排序1
英文摘要

Encephalitis is a disease typically caused by viral infections or autoimmunity. The most common type of autoimmune encephalitis is anti-N-methyl-D-aspartate receptor (NMDAR) antibody-mediated, known as anti-NMDA receptor encephalitis, which is a rare disease. Specific EEG patterns, including extreme delta brush (EDB), have been reported in patients with anti-NMDA receptor encephalitis. The aim of this study was to develop an intelligent diagnostic model for encephalitis based on EEG signals. A total of 131 Participants were selected based on reasonable inclusion criteria and divided into three groups: health control (35 participants), viral encephalitis (58 participants), and anti NMDAR receptor encephalitis (55 participants). Due to the low prevalence of anti-NMDAR receptor encephalitis, it took several years to collect participants' EEG signals while they were in an awake state. EEG signals were collected and analyzed following the international 10-20 system layout. We proposed a model called Temporal Transformer-Spatial Graph Convolutional Network (TT-SGCN), which consists of a Preprocess Module, a Temporal Transformer Module (TTM), and a Spatial Graph Convolutional Module (SGCM). The raw EEG signal was preprocessed according to traditional procedures, including filtering, averaging, and Independent Component Analysis (ICA) method. The EEG signal was then segmented and transformed using short-time Fourier transform (STFT) to produce concatenated power density (CPD) maps, which served as inputs for the proposed model. TTM extracted the time-frequency features of each channel, and SGCM fused these features using graph convolutional methods based on the location of electrodes. The model was evaluated in two experiments: classification of the three groups and pairwise classification among the three groups. The model was trained using two stages and achieved the performance, with an accuracy of 82.23%, recall of 80.75%, precision of 82.51%, and F1 score of 81.23% in the classification of the three groups. The proposed model has the potential to become an intelligent auxiliary diagnostic tool for encephalitis.

语种英语
WOS记录号WOS:001061766800001
出版者FRONTIERS MEDIA SA
源URL[http://ir.opt.ac.cn/handle/181661/96787]  
专题西安光学精密机械研究所_光学影像学习与分析中心
通讯作者Luo, Rong; Wang, Quan
作者单位1.Sichuan Univ, Key Lab Obstet & Gynecol & Pediat Dis & Birth Defe, Minist Educ, Chengdu, Peoples R China
2.Sichuan Univ, West China Univ Hosp 2, Dept Pediat, Chengdu, Peoples R China
3.Chinese Acad Sci, Xian Inst Opt & Precis Mech, Key Lab Biomed Spect Xian, Xian, Peoples R China
4.Univ Chinese Acad Sci, Beijing, Peoples R China
5.Xi An Jiao Tong Univ, Sch Elect & Informat Engn, Xian, Peoples R China
6.Chinese Acad Sci, Xian Inst Opt & Precis Mech XIOPM, Key Lab Spectral Imaging Technol, Xian, Peoples R China
推荐引用方式
GB/T 7714
Dang, Ruochen,Yu, Tao,Hu, Bingliang,et al. Temporal transformer-spatial graph convolutional network: an intelligent classification model for anti N-methyl-D-aspartate receptor encephalitis based on electroencephalogram signal[J]. FRONTIERS MEDIA SA,2023,17.
APA Dang, Ruochen.,Yu, Tao.,Hu, Bingliang.,Wang, Yuqi.,Pan, Zhibin.,...&Wang, Quan.(2023).Temporal transformer-spatial graph convolutional network: an intelligent classification model for anti N-methyl-D-aspartate receptor encephalitis based on electroencephalogram signal.FRONTIERS MEDIA SA,17.
MLA Dang, Ruochen,et al."Temporal transformer-spatial graph convolutional network: an intelligent classification model for anti N-methyl-D-aspartate receptor encephalitis based on electroencephalogram signal".FRONTIERS MEDIA SA 17(2023).

入库方式: OAI收割

来源:西安光学精密机械研究所

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