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Cognitive Benefit of a Multidomain Intervention for Older Adults at Risk of Cognitive Decline: A Cluster- Randomized Controlled Trial

文献类型：期刊论文

作者Liu, Xiaomei1,2; Ma, Zhuoya1,2; Zhu, Xinyi1,2; Zheng, Zhiwei1,2; Li, Juan1,2,7; Fu, Jiangning1,2; Shao, Qi1,2; Han, Xiaoyan3; Wang, Zhihui4; Wang, Xiaoning3
刊名AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY
出版日期2023-03-01
卷号31期号:3页码:197-209
ISSN号1064-7481
关键词Multidomain intervention cognitive decline prevention cluster-randomized controlled trial community-based
DOI10.1016/j.jagp.2022.10.006
通讯作者Li, Juan(lijuan@psych.ac.cn)
英文摘要Objective: We sought to assess cognitive benefits of a community-based multi -domain intervention for improving cognition among older adults at risk of cog-nitive decline (COMBAT). Design: A two-armed cluster-randomized controlled trial. Setting and Participants: Community-dwelling older adults aged 60 years or older and were at risk of cognitive decline (n = 209). Intervention: In this 9-month intervention study, 10 community hospitals in Beijing, China, were randomized (1:1) to receive either a multidomain inter-vention of meditation, cognitive training, exercise, and nutrition counseling or usual care. The intervention was delivered with weekly 1-hour group training sessions and weekly home homework. Measurements: Primary outcome was change in cognition as measured by a composite Z score of seven cognitive tests. Secondary outcomes included subjective cognitive abilities, positive and nega-tive affective experiences, physical activity, and dietary habits. Assessments were administered at baseline, end of the intervention, and 1 year after com-pleting the intervention (1-year follow-up). Results: Immediately after the intervention, the intervention group showed significant enhancement in cogni-tive performance (p = 0.026). The between-group difference in the Z score of change of cognition was 0.20 (95% CI: 0.053, 0.35), with a Hedges' g of 0.40 (95% CI: 0.29, 0.50). However, this cognitive benefit was not significant at
收录类别SCI
WOS关键词MEMORY ; DEMENTIA ; SCALE ; PERFORMANCE ; PREVENTION ; NETWORK
资助项目National Key Research and Development Program of China[2018YFC2000300] ; National Key Research and Development Program of China[2018YFC2001701] ; National Key Research and Development Program of China[2020YFC2003000] ; National Key Research and Development Program of China[2016YFC1305900] ; National Key Research and Development Program of China[2017YFB1401203] ; National Natural Science Foundation of China[32071079] ; National Natural Science Foundation of China[31861133011] ; National Natural Science Foundation of China[31671157] ; National Natural Science Foundation of China[31711530157] ; Youth Innovation Promotion Association of the Chinese Academy of Sciences[2020089] ; Beijing Municipal Science & Technology Commission[Z171100008217006] ; Beijing Municipal Science & Technology Commission[Z171100000117006] ; Scientific Foundation of Institute of Psychology Chinese Academy of Sciences[E2CX3715CX]
WOS研究方向Geriatrics & Gerontology ; Psychiatry
语种英语
出版者ELSEVIER SCIENCE INC
WOS记录号WOS:000991738500001
资助机构National Key Research and Development Program of China ; National Natural Science Foundation of China ; Youth Innovation Promotion Association of the Chinese Academy of Sciences ; Beijing Municipal Science & Technology Commission ; Scientific Foundation of Institute of Psychology Chinese Academy of Sciences
源URL[http://ir.psych.ac.cn/handle/311026/45443]  
专题心理研究所_中国科学院心理健康重点实验室
通讯作者Li, Juan
作者单位1.Chinese Acad Sci, Inst Psychol, Ctr Aging Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China
2.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
3.Chaoyang Dist Ctr Dis Control & Prevent, Beijing, Peoples R China
4.Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China
5.Karolinska Inst, Aging Res Ctr, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden
6.Stockholm Univ, Stockholm, Sweden
7.Chinese Acad Sci, Inst Psychol, 16 Lincui Rd, Beijing 100101, Peoples R China
推荐引用方式
GB/T 7714		 Liu, Xiaomei,Ma, Zhuoya,Zhu, Xinyi,et al. Cognitive Benefit of a Multidomain Intervention for Older Adults at Risk of Cognitive Decline: A Cluster- Randomized Controlled Trial[J]. AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY,2023,31(3):197-209.
APA Liu, Xiaomei.,Ma, Zhuoya.,Zhu, Xinyi.,Zheng, Zhiwei.,Li, Juan.,...&Qiu, Chengxuan.(2023).Cognitive Benefit of a Multidomain Intervention for Older Adults at Risk of Cognitive Decline: A Cluster- Randomized Controlled Trial.AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY,31(3),197-209.
MLA Liu, Xiaomei,et al."Cognitive Benefit of a Multidomain Intervention for Older Adults at Risk of Cognitive Decline: A Cluster- Randomized Controlled Trial".AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY 31.3(2023):197-209.

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来源：心理研究所

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