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Evaluation of Electroconvulsive Therapy in Adolescents With Major Depressive and Bipolar Disorders A Retrospective Analysis

文献类型：期刊论文

作者Shao, Wen1; Zheng, Yi2; Li, Qingxia3; Shao, Kangning1,4; Zhao, Fujun5; Guan, Lin2; Zhang, Zhixia2; Li, Fenghua1
刊名JOURNAL OF ECT
出版日期2023-06-01
卷号39期号:2页码:111-116
ISSN号1095-0680
关键词adolescents ECT mood disorder safety treatment outcome
DOI10.1097/YCT.0000000000000894
通讯作者Li, Fenghua(lifh@psych.ac.cn)
英文摘要ObjectiveThis study aims to provide an evaluation of electroconvulsive therapy (ECT) in hospitalized adolescents with major depressive and bipolar disorders by examining its treatment outcomes as well as comparing it with outcomes of hospitalized patients, treated as usual (TAU).MethodsThis is a retrospective study based on medical records documented between April 2011 and December 2017 from Beijing An Ding Hospital. Patients were diagnosed according to the International Classification of Diseases, Tenth Revision. The study included 288 inpatients, with 2 groups of 171 patients treated by ECT and 117 TAU. The primary outcome was measured using the severity subscale of Clinical Global Impression. Mann-Whitney U test, chi(2) test, and linear regression with mixed models were used to analyze the data.ResultsSymptom severity reduced significantly for both groups (beta = -0.62, t(975.93) = -20.54, P < 0.001). The TAU group was associated with lower score on the severity subscale of Clinical Global Impression (beta = 0.28, t(980.32) = 8.36, P < 0.001). The ECT group had a higher remission rate (28.65%) than the TAU group (16.24%), but the time required for remission was longer (U [N-ECT = 49, N-TAU = 19] = 615, z = 2.10, P = 0.04). Adverse events of ECT were barely observed.ConclusionElectroconvulsive therapy is an efficacious and safe treatment for adolescents. However, as the superiority in efficacy was not evident in ECT group, its prescription should be prudently considered for younger patients who respond well to other treatments.
收录类别SCI
WOS关键词RATING-SCALE ; VALIDITY ; ANXIETY ; SPEED ; MANIA
WOS研究方向Behavioral Sciences ; Psychiatry
语种英语
出版者LIPPINCOTT WILLIAMS & WILKINS
WOS记录号WOS:000995034200013
源URL[http://ir.psych.ac.cn/handle/311026/45449]  
专题心理研究所_中国科学院心理健康重点实验室
通讯作者Li, Fenghua
作者单位1.Chinese Acad Sci, Inst Psychol, Key Lab Mental Hlth, Beijing, Peoples R China
2.Capital Med Univ, Beijing Ding Hosp, Beijing, Peoples R China
3.South China Normal Univ, Sch Psychol, Guangzhou, Guangdong, Peoples R China
4.Zhengzhou Univ, Affiliated Hosp 2, Zhengzhou, Peoples R China
5.Capital Med Univ, Beijing Childrens Hosp, Natl Ctr Childrens Hlth, Beijing, Peoples R China
推荐引用方式
GB/T 7714		 Shao, Wen,Zheng, Yi,Li, Qingxia,et al. Evaluation of Electroconvulsive Therapy in Adolescents With Major Depressive and Bipolar Disorders A Retrospective Analysis[J]. JOURNAL OF ECT,2023,39(2):111-116.
APA Shao, Wen.,Zheng, Yi.,Li, Qingxia.,Shao, Kangning.,Zhao, Fujun.,...&Li, Fenghua.(2023).Evaluation of Electroconvulsive Therapy in Adolescents With Major Depressive and Bipolar Disorders A Retrospective Analysis.JOURNAL OF ECT,39(2),111-116.
MLA Shao, Wen,et al."Evaluation of Electroconvulsive Therapy in Adolescents With Major Depressive and Bipolar Disorders A Retrospective Analysis".JOURNAL OF ECT 39.2(2023):111-116.

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来源：心理研究所

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