Prevalence and influencing factors of suicide in first-episode and drug-naive young major depressive disorder patients with impaired fasting glucose: a cross-sectional study
文献类型：期刊论文
| 作者 | Li, Yifan1; Liao, Zhenjiang1; Huang, Qiuping2; Wang, Qianjin1; Ren, Honghong1; Chen, Xinxin1; Lin, Shuhong1; Wang, Chenhan3; Tang, Ying1; Hao, Jingyue1 |
| 刊名 | FRONTIERS IN PSYCHIATRY
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| 出版日期 | 2023-06-09 |
| 卷号 | 14页码:10 |
| ISSN号 | 1664-0640 |
| 关键词 | anxiety depression disorder suicide attempts impaired fasting glucose thyroid antibodies blood lipids |
| DOI | 10.3389/fpsyt.2023.1171814 |
| 通讯作者 | Shen, Hongxian(shenhx2018@csu.edu.cn) ; Zhang, Xiangyang(zhangxy@psych.ac.cn) |
| 英文摘要 | BackgroundAn association exists between major depression disorder (MDD), suicide attempts, and glucose metabolism, but suicide attempts in young MDD patients with comorbid impaired fasting glucose (IFG) have been less well studied. The purpose of this study was to examine the prevalence and risk factors for suicide attempts in young, first-episode, drug-naive (FEDN) MDD patients with comorbid IFG. MethodsWe recruited 917 young patients with FEDN MDD, 116 of whom were judged to have combined IFG because their blood glucose was >6.0. We collected anthropological and clinical data on all of them. The Hamilton Depression Scale (HAMD) score, the Hamilton Anxiety Scale (HAMA) score and the Positive and Negative Syndrome Scale (PANSS) positive subscale score were used to assess their clinical symptoms. Blood glucose, plasma thyroid function and lipid indicators were measured. ResultsThe prevalence of suicide attempts in young MDD patients with IFG was 32.8% (38/116). Furthermore, among young MDD patients with comorbid IFG, suicide attempters had more severe depression and anxiety symptoms, more comorbid psychotic symptom, higher levels of antibody of thyroid stimulating hormone and thyroid peroxidases (TPOAb), and more severe lipid metabolism disorders than those without suicide attempts. In addition, HAMA scores and TPOAb were independently associated with suicide attempts in young patients with FEDN MDD. ConclusionOur study suggests that young MDD patients with IFG have a high rate of suicide attempts. Some clinical symptoms and thyroid function parameters may be the risk factor for suicide attempts in young MDD patients with impaired glucose metabolism. |
| 收录类别 | SCI |
| WOS关键词 | COMORBID ANXIETY ; RISK-FACTORS ; SELF-HARM ; IDEATION ; CLASSIFICATION ; ASSOCIATION ; ATTEMPTERS ; BEHAVIORS ; DEATH ; SCALE |
| WOS研究方向 | Psychiatry |
| 语种 | 英语 |
| 出版者 | FRONTIERS MEDIA SA |
| WOS记录号 | WOS:001013089400001 |
| 源URL | [http://ir.psych.ac.cn/handle/311026/45605]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 通讯作者 | Shen, Hongxian; Zhang, Xiangyang |
| 作者单位 | 1.Cent South Univ, Xiangya Hosp 2, Natl Clin Res Ctr Mental Disorders, Dept Psychiat, Changsha, Hunan, Peoples R China 2.Hunan Univ Chinese Med, Sch Humanities & Management, Dept Appl Psychol, Changsha, Peoples R China 3.Lanzhou Univ, Clin Med Coll 1, Lanzhou, Peoples R China 4.Chinese Acad Sci, Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Yifan,Liao, Zhenjiang,Huang, Qiuping,et al. Prevalence and influencing factors of suicide in first-episode and drug-naive young major depressive disorder patients with impaired fasting glucose: a cross-sectional study[J]. FRONTIERS IN PSYCHIATRY,2023,14:10. |
| APA | Li, Yifan.,Liao, Zhenjiang.,Huang, Qiuping.,Wang, Qianjin.,Ren, Honghong.,...&Zhang, Xiangyang.(2023).Prevalence and influencing factors of suicide in first-episode and drug-naive young major depressive disorder patients with impaired fasting glucose: a cross-sectional study.FRONTIERS IN PSYCHIATRY,14,10. |
| MLA | Li, Yifan,et al."Prevalence and influencing factors of suicide in first-episode and drug-naive young major depressive disorder patients with impaired fasting glucose: a cross-sectional study".FRONTIERS IN PSYCHIATRY 14(2023):10. |
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来源：心理研究所
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