Identifying subgroups of attention-deficit/hyperactivity disorder from the psychopathological and neuropsychological profiles
文献类型：期刊论文
| 作者 | Zhang, Shan-hong1; Yang, Tian-xiao2,3 ; Wu, Zhao-min1; Wang, Yu-feng4; Lui, Simon S. Y.5; Yang, Bin-rang1,6; Chan, Raymond C. K.2,3
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| 刊名 | JOURNAL OF NEUROPSYCHOLOGY
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| 出版日期 | 2023-06-28 |
| 页码 | 17 |
| ISSN号 | 1748-6645 |
| 关键词 | ADHD cluster analysis executive functions externalizing internalizing |
| DOI | 10.1111/jnp.12334 |
| 通讯作者 | Yang, Bin-rang(ybinrang@126.com) |
| 英文摘要 | The Research Domain Criteria (RDoC) advocates the dimensional approach in characterizing mental disorders. We followed RDoC to characterize children with ADHD using profiling based on the cognitive and psychopathological domains. We aimed to identify and validate ADHD subtypes with different clinical characteristics and functional impairments. We recruited 362 drug-naive children with ADHD and 103 typically developing controls. The cluster analysis was used to identify subgroups based on the Child Behaviour Checklist (CBCL) and the Behaviour Rating Inventory of Executive Function (BRIEF). The subgroups' clinical characteristics and functional impairments were assessed using the WEISS Functional Impairment Rating Scale-Parent Report (WFIRS-P) and the Conners Parent Symptom Questionnaire (PSQ). The cluster analysis yielded four subgroups: (1) ADHD with severe impairment in psychopathology and executive functions (EF), (2) ADHD with mild executive dysfunctions and normal-level psychopathology, (3) ADHD with severe externalizing problems and (4) ADHD with severe executive dysfunctions. These subgroups showed different clinical characteristics and degrees of functional impairment. The EF impairment group displayed more serious learning problems and worse life skills than the externalizing group. The two groups with externalizing problems (i.e. the severe impairment group and the externalizing group) both exhibited higher rates of the combined subtype of ADHD and higher rates of comorbid ODD. Different subtypes of ADHD displayed different profiles of internalizing and externalizing problems and levels of executive dysfunctions. In particular, the subtype with severe impairment in EF exhibited more learning problems and worse life skills, suggesting EF is a critical target for intervention in children with ADHD. |
| 收录类别 | SCI |
| WOS关键词 | DEFICIT HYPERACTIVITY DISORDER ; LATENT CLASS ANALYSIS ; EXECUTIVE FUNCTION ; SELF-REGULATION ; CHILDREN ; ADHD ; PERFORMANCE ; METAANALYSIS ; CHILDHOOD ; SKILLS |
| 资助项目 | Sanming Project of Medicine in Shenzhen[SZSM201612036] ; Guangdong High - level Hospital Construction Fund ; National Natural Science Foundation of China[82101613] ; Basic and Applied Basic Research Project of Guangdong Province of China[2019A 1515110700] |
| WOS研究方向 | Psychology |
| 语种 | 英语 |
| 出版者 | WILEY |
| WOS记录号 | WOS:001018676100001 |
| 资助机构 | Sanming Project of Medicine in Shenzhen ; Guangdong High - level Hospital Construction Fund ; National Natural Science Foundation of China ; Basic and Applied Basic Research Project of Guangdong Province of China |
| 源URL | [http://ir.psych.ac.cn/handle/311026/45621]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 通讯作者 | Yang, Bin-rang |
| 作者单位 | 1.Shenzhen Childrens Hosp, Shenzhen, Peoples R China 2.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, Beijing, Peoples R China 3.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China 4.Peking Univ Sixth Hosp, Inst Mental Hlth, Natl Clin Res Ctr Mental Disorders, Beijing, Peoples R China 5.Univ Hong Kong, Sch Clin Med, Dept Psychiat, Hong Kong, Peoples R China 6.Shenzhen Childrens Hosp, 7019 Yitian Rd, Shenzhen 518038, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Shan-hong,Yang, Tian-xiao,Wu, Zhao-min,et al. Identifying subgroups of attention-deficit/hyperactivity disorder from the psychopathological and neuropsychological profiles[J]. JOURNAL OF NEUROPSYCHOLOGY,2023:17. |
| APA | Zhang, Shan-hong.,Yang, Tian-xiao.,Wu, Zhao-min.,Wang, Yu-feng.,Lui, Simon S. Y..,...&Chan, Raymond C. K..(2023).Identifying subgroups of attention-deficit/hyperactivity disorder from the psychopathological and neuropsychological profiles.JOURNAL OF NEUROPSYCHOLOGY,17. |
| MLA | Zhang, Shan-hong,et al."Identifying subgroups of attention-deficit/hyperactivity disorder from the psychopathological and neuropsychological profiles".JOURNAL OF NEUROPSYCHOLOGY (2023):17. |
入库方式： OAI收割
来源：心理研究所
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