The impact of pre-adulthood urbanicity on hippocampal subfield volumes and neurocognitive abilities in young adults
文献类型：期刊论文
| 作者 | Liu, Mengge1,2; Han, Tong3; Wu, Yue4; Cheng, Jingliang5; Zhang, Longjiang6; Zhang, Bing7; Zuo, Xi-Nian8,9 ; Zhu, Wenzhen10; Qiu, Shijun11; Geng, Zuojun12
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| 刊名 | ENVIRONMENT INTERNATIONAL
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| 出版日期 | 2023-04-01 |
| 卷号 | 174页码:11 |
| 关键词 | Hippocampal subfields Urban Neurocognition Remote sensing Neuroimaging |
| ISSN号 | 0160-4120 |
| DOI | 10.1016/j.envint.2023.107905 |
| 通讯作者 | Liao, Wei-Hua(ouwenliao@163.com) ; Wang, Dawei(daweiwangtj@126.com) ; Yu, Chunshui(chunshuiyu@tmu.edu.cn) |
| 英文摘要 | Background: Urbanicity refers to the conditions that are particular to urban areas and is a growing environmental challenge that may affect hippocampus and neurocognition. This study aimed to investigate the effects of the average pre-adulthood urbanicity on hippocampal subfield volumes and neurocognitive abilities as well as the sensitive age windows of the urbanicity effects.Participants and methods: We included 5,390 CHIMGEN participants (3,538 females; age: 23.69 +/- 2.26 years, range: 18-30 years). Pre-adulthood urbanicity of each participant was defined as the average value of annual night-time light (NL) or built-up% from age 0-18, which were extracted from remote-sensing satellite data based on annual residential coordinates of the participants. The hippocampal subfield volumes were calculated based on structural MRI and eight neurocognitive measures were assessed. The linear regression was applied to investigate the associations of pre-adulthood NL with hippocampal subfield volumes and neurocognitive abili-ties, mediation models were used to find the underlying pathways among urbanicity, hippocampus and neuro-cognition, and distributed lag models were used to identify sensitive age windows of urbanicity effect.Results: Higher pre-adulthood NL was associated with greater volumes in the left (beta = 0.100, 95%CI: [0.075, 0.125]) and right (0.078, [0.052, 0.103]) fimbria and left subiculum body (0.045, [0.020, 0.070]) and better neurocognitive abilities in information processing speed (-0.212, [-0.240,-0.183]), working memory (0.085, [0.057, 0.114]), episodic memory (0.107, [0.080, 0.135]), and immediate (0.094, [0.065, 0.123]) and delayed (0.087, [0.058, 0.116]) visuospatial recall, and hippocampal subfield volumes and visuospatial memory showed bilateral mediations for the urbanicity effects. Urbanicity effects were greatest on the fimbria in preschool and adolescence, on visuospatial memory and information processing from childhood to adolescence and on working memory after 14 years.Conclusion: These findings improve our understanding of the impact of urbanicity on hippocampus and neuro-cognitive abilities and will benefit for designing more targeted intervention for neurocognitive improvement. |
| 收录类别 | SCI |
| WOS关键词 | CORTICAL THICKNESS ; WHITE-MATTER ; MEMORY ; ADOLESCENCE ; BRAIN ; NEUROGENESIS ; CHILDHOOD ; STRESS ; HARMONIZATION ; SCHIZOPHRENIA |
| 资助项目 | National Key Research and Devel-opment Program of China[2018YFC1314300] ; National Natural Science Foundation of China[82030053] ; National Natural Science Foundation of China[81425013] ; Tianjin Key Medical Discipline (Specialty) Construction Project[TJYXZDXK-001A] |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:000989778800001 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| 资助机构 | National Key Research and Devel-opment Program of China ; National Natural Science Foundation of China ; Tianjin Key Medical Discipline (Specialty) Construction Project |
| 源URL | [http://ir.psych.ac.cn/handle/311026/45556]  |
| 专题 | 心理研究所_认知与发展心理学研究室 |
| 通讯作者 | Liao, Wei-Hua; Wang, Dawei; Yu, Chunshui |
| 作者单位 | 1.Tianjin Med Univ Gen Hosp, Dept Radiol, Tianjin 300052, Peoples R China 2.Tianjin Med Univ Gen Hosp, Tianjin Key Lab Funct Imaging, Tianjin 300052, Peoples R China 3.Tianjin Huanhu Hosp, Dept Radiol, Tianjin 300350, Peoples R China 4.Fudan Univ, Huashan Hosp, Dept Radiol, Shanghai 200040, Peoples R China 5.Zhengzhou Univ, Dept Magnet Resonance Imaging, Affiliated Hosp 1, Zhengzhou 450052, Peoples R China 6.Nanjing Univ, Sch Med, Jinling Hosp, Dept Med Imaging, Nanjing 210002, Peoples R China 7.Nanjing Univ, Sch Med, Drum Tower Hosp, Dept Radiol, Nanjing 210008, Peoples R China 8.Beijing Normal Univ, IDG McGovern Inst Brain Res, Beijing 100875, Peoples R China 9.Chinese Acad Sci, Inst Psychol, Beijing 100101, Peoples R China 10.Huazhong Univ Sci & Technol, Dept Radiol, Tongji Hosp, Tongji Med Coll, Wuhan 430030, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Mengge,Han, Tong,Wu, Yue,et al. The impact of pre-adulthood urbanicity on hippocampal subfield volumes and neurocognitive abilities in young adults[J]. ENVIRONMENT INTERNATIONAL,2023,174:11. |
| APA | Liu, Mengge.,Han, Tong.,Wu, Yue.,Cheng, Jingliang.,Zhang, Longjiang.,...&Yu, Chunshui.(2023).The impact of pre-adulthood urbanicity on hippocampal subfield volumes and neurocognitive abilities in young adults.ENVIRONMENT INTERNATIONAL,174,11. |
| MLA | Liu, Mengge,et al."The impact of pre-adulthood urbanicity on hippocampal subfield volumes and neurocognitive abilities in young adults".ENVIRONMENT INTERNATIONAL 174(2023):11. |
入库方式： OAI收割
来源：心理研究所
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