Voice Patterns as Markers of Schizophrenia: Building a Cumulative Generalizable Approach Via a Cross-Linguistic and Meta-analysis Based Investigation
文献类型：期刊论文
| 作者 | Parola, Alberto1,2,3,11; Simonsen, Arndis2,4; Lin, Jessica Mary1,2; Zhou, Yuan5 ; Wang, Huiling6; Ubukata, Shiho7; Koelkebeck, Katja8,9; Bliksted, Vibeke2,4; Fusaroli, Riccardo1,2,10
|
| 刊名 | SCHIZOPHRENIA BULLETIN
 |
| 出版日期 | 2023-03-22 |
| 卷号 | 49期号:SUPP2页码:S125-S141 |
| ISSN号 | 0586-7614 |
| 关键词 | vocal analysis psychosis speech signal digital phenotyping prosody negative symptoms |
| DOI | 10.1093/schbul/sbac128 |
| 通讯作者 | Parola, Alberto(alberto.parol@gmail.com) |
| 英文摘要 | Background and Hypothesis Voice atypicalities are potential markers of clinical features of schizophrenia (eg, negative symptoms). A recent meta-analysis identified an acoustic profile associated with schizophrenia (reduced pitch variability and increased pauses), but also highlighted shortcomings in the field: small sample sizes, little attention to the heterogeneity of the disorder, and to generalizing findings to diverse samples and languages. Study Design We provide a critical cumulative approach to vocal atypicalities in schizophrenia, where we conceptually and statistically build on previous studies. We aim at identifying a cross-linguistically reliable acoustic profile of schizophrenia and assessing sources of heterogeneity (symptomatology, pharmacotherapy, clinical and social characteristics). We relied on previous meta-analysis to build and analyze a large cross-linguistic dataset of audio recordings of 231 patients with schizophrenia and 238 matched controls (>4000 recordings in Danish, German, Mandarin and Japanese). We used multilevel Bayesian modeling, contrasting meta-analytically informed and skeptical inferences. Study Results We found only a minimal generalizable acoustic profile of schizophrenia (reduced pitch variability), while duration atypicalities replicated only in some languages. We identified reliable associations between acoustic profile and individual differences in clinical ratings of negative symptoms, medication, age and gender. However, these associations vary across languages. Conclusions The findings indicate that a strong cross-linguistically reliable acoustic profile of schizophrenia is unlikely. Rather, if we are to devise effective clinical applications able to target different ranges of patients, we need first to establish larger and more diverse cross-linguistic datasets, focus on individual differences, and build self-critical cumulative approaches. |
| 收录类别 | SCI |
| WOS关键词 | NEGATIVE SYMPTOMS ; MIND ; HETEROGENEITY ; DEPRESSION ; SCALE ; DISORDERS ; PSYCHOSIS ; DEFICITS ; PANSS |
| 资助项目 | Marie Sklodowska-Curie Actions- H2020-MSCA-IF-2018[832518] ; Carlsberg Foundation ; Japan Society for the Promotion of Science (JSPS)[PE 07550] ; Interacting Minds Center, Aarhus University |
| WOS研究方向 | Psychiatry |
| 语种 | 英语 |
| 出版者 | OXFORD UNIV PRESS |
| WOS记录号 | WOS:000989362600006 |
| 资助机构 | Marie Sklodowska-Curie Actions- H2020-MSCA-IF-2018 ; Carlsberg Foundation ; Japan Society for the Promotion of Science (JSPS) ; Interacting Minds Center, Aarhus University |
| 源URL | [http://ir.psych.ac.cn/handle/311026/45420]  |
| 专题 | 心理研究所_社会与工程心理学研究室 |
| 通讯作者 | Parola, Alberto |
| 作者单位 | 1.Aarhus Univ, Dept Linguist Cognit Sci & Semiot, Aarhus, Denmark 2.Aarhus Univ, Inst Culture & Soc, Interacting Minds Ctr, Aarhus, Denmark 3.Univ Turin, Dept Psychol, Turin, Italy 4.Aarhus Univ, Dept Clin Med, Psychosis Res Unit, Aarhus, Denmark 5.Chinese Acad Sci, Inst Psychol, Beijing, Peoples R China 6.Wuhan Univ, Dept Psychiat, Renmin Hosp, Wuhan, Peoples R China 7.Kyoto Univ, Dept Psychiat, Kyoto, Japan 8.Inst Univ Duisburg Essen, Hosp Essen, Hosp, Dept Psychiat & Psychotherapy, Essen, Germany 9.Univ Duisburg Essen, Ctr Translat Neuroand Behav Sci C TNBS, Essen, Germany 10.Univ Penn, Linguist Data Consortium, Philadelphia, PA USA |
| 推荐引用方式 GB/T 7714 | Parola, Alberto,Simonsen, Arndis,Lin, Jessica Mary,et al. Voice Patterns as Markers of Schizophrenia: Building a Cumulative Generalizable Approach Via a Cross-Linguistic and Meta-analysis Based Investigation[J]. SCHIZOPHRENIA BULLETIN,2023,49(SUPP2):S125-S141. |
| APA | Parola, Alberto.,Simonsen, Arndis.,Lin, Jessica Mary.,Zhou, Yuan.,Wang, Huiling.,...&Fusaroli, Riccardo.(2023).Voice Patterns as Markers of Schizophrenia: Building a Cumulative Generalizable Approach Via a Cross-Linguistic and Meta-analysis Based Investigation.SCHIZOPHRENIA BULLETIN,49(SUPP2),S125-S141. |
| MLA | Parola, Alberto,et al."Voice Patterns as Markers of Schizophrenia: Building a Cumulative Generalizable Approach Via a Cross-Linguistic and Meta-analysis Based Investigation".SCHIZOPHRENIA BULLETIN 49.SUPP2(2023):S125-S141. |
入库方式： OAI收割
来源：心理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。