Soybean oil-based polyurethane networks as candidate biomaterials: Synthesis and biocompatibility
文献类型：期刊论文
| 作者 | Miao, Shida; Sun, Lijing; Wang, Ping; Liu, Ruina; Su, Zhiguo; Zhang, Songping |
| 刊名 | EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
 |
| 出版日期 | 2012-10-01 |
| 卷号 | 114期号:si页码:1165-1174 |
| 关键词 | Biocompatibility Lactic acid Polyol Polyurethane Soybean oil |
| 通讯作者 | Zhang, SP |
| 英文摘要 | Biobased polymeric materials are gaining increasing attention in biomedical areas. Here, we report a new class of biocompatible polyurethanes prepared from soybean oil-based polyol that was synthesized by ring-opening reaction of epoxidized monoglyceride (EMG) with lactic acid. By adjusting the molar ratio of hydroxyl to isocyanate group and the content of chain extender, soybean oil-based polyurethanes with tensile strength of 9.3027.1?MPa and elongation at break of 74.1110.7% were prepared, while usual lipid-based polyurethanes with the same 1,6-diisocyanatohexane as reactant hardly have tensile strength higher than 5?MPa. Mouse fibroblast cells (L-929) showed good adhesion and growth behavior on the polyurethane samples with more hydrophilic surfaces, and the cell viabilities of more than 50% were achieved with commercial tissue culture polystyrene (TCPS) disk as control. The good mechanical property and biocompatibility of the soybean oil-based polyurethanes will make them suitable for wide range of potential biomedical applications. Practical applications: The synthesized soybean oil-based polyurethanes have adjustable tensile strengths from 9.3027.1?MPa and elongation at break of 74.1110.7%. Along with their good biocompatibility, the polyurethanes can potentially replace wide range of part of petroleum-based polymeric materials, particularly as biomedical materials. |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000310261400010 |
| 公开日期 | 2013-10-11 |
| 版本 | 出版稿 |
| 源URL | [http://ir.ipe.ac.cn/handle/122111/3175]  |
| 专题 | 过程工程研究所_生化工程国家重点实验室 |
| 推荐引用方式 GB/T 7714 | Miao, Shida,Sun, Lijing,Wang, Ping,et al. Soybean oil-based polyurethane networks as candidate biomaterials: Synthesis and biocompatibility[J]. EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY,2012,114(si):1165-1174. |
| APA | Miao, Shida,Sun, Lijing,Wang, Ping,Liu, Ruina,Su, Zhiguo,&Zhang, Songping.(2012).Soybean oil-based polyurethane networks as candidate biomaterials: Synthesis and biocompatibility.EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY,114(si),1165-1174. |
| MLA | Miao, Shida,et al."Soybean oil-based polyurethane networks as candidate biomaterials: Synthesis and biocompatibility".EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY 114.si(2012):1165-1174. |
入库方式： OAI收割
来源：过程工程研究所
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